{"product_id":"creatine-and-creatine-kinase-in-health-and-disease-expert","title":"Creatine and Creatine Kinase in Health and Disease - Expert","description":"\u003cp\u003eIn this review of Creatine and Creatine Kinase in Health and Disease the reviewer finds a focused, scholarly resource aimed at readers who want a deep mechanistic account of creatine biology. The book is most valuable for clinicians, researchers and advanced students studying the links between creatine, brain function and neurodegeneration; its single biggest reason to buy is the thorough treatment of biochemical interplay and clinical implications that are rarely assembled in one volume. This review highlights the book's emphasis on inborn errors of creatine metabolism, neuroprotection, and the pharmacokinetics and safety of supplementation.\u003c\/p\u003e\n\u003ch2\u003eKey Features\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFocused biochemical analysis:\u003c\/strong\u003e Detailed exploration of the interplay between \u003cstrong\u003ecreatine\u003c\/strong\u003e and \u003cstrong\u003ecreatine kinase\u003c\/strong\u003e clarifies mechanisms relevant to brain and muscle physiology.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClinical relevance:\u003c\/strong\u003e The book documents the recently identified \u003cstrong\u003ecerebral creatine deficiency syndromes\u003c\/strong\u003e, offering clinicians a concise reference on diagnosis and pathophysiology.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeurodegeneration and neuroprotection:\u003c\/strong\u003e Dedicated chapters discuss how creatine systems relate to neurodegenerative disease and potential protective strategies.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSupplementation coverage:\u003c\/strong\u003e A practical treatment of pharmacokinetics and the safety profile of oral creatine informs decisions about therapeutic and performance use.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSystems biology perspective:\u003c\/strong\u003e Emerging systems biology approaches are outlined to help integrate pleiotropic effects across tissues and disease states.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWho It's For\u003c\/h2\u003e\n\u003cp\u003eThe book is best suited to neurologists, clinical researchers, and advanced graduate students who need a rigorous, referenced account of creatine metabolism and its clinical syndromes; its tone assumes familiarity with biochemical and clinical terminology. It is also useful for translational researchers exploring creatine as a therapeutic or neuroprotective agent.\u003c\/p\u003e\n\u003cp\u003eReaders seeking a general consumer guide to dietary creatine, simple training tips, or an introductory popular science treatment should look elsewhere, because the volume emphasizes mechanistic detail and clinical context rather than beginner-level supplementation advice.\u003c\/p\u003e\n\u003ch2\u003ePros \u0026amp; Cons\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003ePros\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eComprehensive coverage of the biochemical relationship between \u003cstrong\u003ecreatine\u003c\/strong\u003e and \u003cstrong\u003ecreatine kinase\u003c\/strong\u003e, useful for specialists.\u003c\/li\u003e\n\u003cli\u003eClear discussion of \u003cstrong\u003ecerebral creatine deficiency syndromes\u003c\/strong\u003e, filling a gap in clinical literature.\u003c\/li\u003e\n\u003cli\u003eBalanced treatment of pharmacokinetics and safety, which aids evidence-based decisions about supplementation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eCons\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHighly technical writing may be dense for non-specialists and casual readers.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003eTitle\u003c\/td\u003e\n\u003ctd\u003eCreatine and Creatine Kinase in Health and Disease\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSeries\u003c\/td\u003e\n\u003ctd\u003eSubcellular Biochemistry, 46\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAuthors \/ Editors\u003c\/td\u003e\n\u003ctd\u003eGajja S. Salomons, Markus Wyss\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePrimary topics\u003c\/td\u003e\n\u003ctd\u003eCreatine metabolism, creatine kinase, neurodegeneration, supplementation\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eClinical focus\u003c\/td\u003e\n\u003ctd\u003eCerebral creatine deficiency syndromes and neuroprotection\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eScope\u003c\/td\u003e\n\u003ctd\u003eBiochemical mechanisms, pharmacokinetics, safety, systems biology approaches\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003ch2\u003eOur Verdict\u003c\/h2\u003e\n\u003cp\u003eFor specialists who need a concentrated, evidence-based account of creatine systems in brain and muscle, this volume is a strong value: it compiles biochemical detail, clinical syndrome descriptions and thoughtful discussion of supplementation safety in one place. Those outside clinical or research roles will find it more reference than light reading, but for its target audience the book is an authoritative, useful resource.\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDoes this book cover clinical syndromes linked to creatine?\u003c\/strong\u003e\u003cbr\u003eYes, it includes detailed discussion of the recently identified cerebral creatine deficiency syndromes and their clinical implications.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIs the book suitable for general fitness readers?\u003c\/strong\u003e\u003cbr\u003eNo, the text is technical and oriented to clinicians and researchers rather than casual supplement users.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes it discuss safety of oral creatine?\u003c\/strong\u003e\u003cbr\u003eYes, the book reviews pharmacokinetics and the safety profile of oral creatine supplementation within clinical and research contexts.\u003c\/p\u003e","brand":"Gajja S. Salomons, Markus Wyss","offers":[{"title":"Default Title","offer_id":48187126579419,"sku":"9048176522","price":169.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0724\/1043\/1707\/files\/516Xx7s2CmL._SL1239.jpg?v=1769615028","url":"https:\/\/gearmusthave.com\/products\/creatine-and-creatine-kinase-in-health-and-disease-expert","provider":"GearMustHave","version":"1.0","type":"link"}