{"product_id":"modeling-peptide-protein-interactions-methods-and-protocols","title":"Modeling Peptide-Protein Interactions: Methods and Protocols","description":"\u003cp\u003eIn this review of Modeling Peptide-Protein Interactions: Methods and Protocols the bottom line is clear: this volume is best for researchers and advanced graduate students who need a practical, method-focused reference for peptide docking and design. The book collects tested protocols and tool-focused chapters that let a reader move from binding site prediction to flexible docking and design workflows, and it is written in the familiar Methods in Molecular Biology format so users get stepwise procedures rather than high-level theory. For anyone implementing peptide-protein experiments or computational pipelines, this book saves time by describing concrete tools and approaches.\u003c\/p\u003e\n\u003ch2\u003eKey Features\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePractical protocols:\u003c\/strong\u003e Step-by-step methods guide a reader through experimental and computational workflows so protocols can be adapted for laboratory use.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBinding site prediction:\u003c\/strong\u003e Coverage of ACCLUSTER and PeptiMap helps users locate likely peptide binding sites before running docking experiments.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDocking approaches:\u003c\/strong\u003e Descriptions of AnchorDock, ATTRACT, HADDOCK and FlexPepDock present options for blind and flexible peptide docking to proteins.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInteraction discovery:\u003c\/strong\u003e The LoopFinder chapter explains how to identify loop-mediated protein-protein contacts that may mediate peptide recognition.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDesign tools:\u003c\/strong\u003e The PinaColada workflow shows practical steps for designing peptide binders and tuning binding specificity.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWho It's For\u003c\/h2\u003e\n\u003cp\u003eThe primary audience is computational structural biologists and experimental molecular biologists who already have familiarity with protein structure and want actionable methods for peptide docking and design. Laboratory scientists running peptide binding or inhibition studies will find the procedural format and tool comparisons especially useful.\u003c\/p\u003e\n\u003cp\u003eIt is less suitable for complete beginners seeking general background in protein biophysics or for readers who want broad conceptual surveys without hands-on protocols. Those needing an introductory textbook on protein structure should look elsewhere.\u003c\/p\u003e\n\u003ch2\u003ePros \u0026amp; Cons\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003ePros\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFocused, stepwise protocols make it straightforward to reproduce suggested workflows in the lab or on the desktop.\u003c\/li\u003e\n\u003cli\u003eCoverage of multiple, complementary tools gives practical choices for binding site prediction and docking strategies.\u003c\/li\u003e\n\u003cli\u003eIncludes both docking and design perspectives, linking prediction tools to peptide inhibitor design approaches.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eCons\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAssumes prior knowledge of structural biology and computational tools, so it is not a beginner primer.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003eTitle\u003c\/td\u003e\n\u003ctd\u003eModeling Peptide-Protein Interactions: Methods and Protocols\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSeries\u003c\/td\u003e\n\u003ctd\u003eMethods in Molecular Biology\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eEditors\/Authors\u003c\/td\u003e\n\u003ctd\u003eOra Schueler-Furman, Nir London\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTopics covered\u003c\/td\u003e\n\u003ctd\u003eBinding site prediction, peptide-protein docking, design of specificity, inhibitory peptide design\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTools described\u003c\/td\u003e\n\u003ctd\u003eACCLUSTER, PeptiMap, AnchorDock, ATTRACT, HADDOCK, FlexPepDock, LoopFinder, PinaColada\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat\u003c\/td\u003e\n\u003ctd\u003eProtocol-focused methods volume\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003ch2\u003eOur Verdict\u003c\/h2\u003e\n\u003cp\u003eThis Methods in Molecular Biology volume is a practical, well-structured resource for researchers who need tested protocols and tool recommendations for peptide binding prediction, docking and design. It is good value for labs and computational groups ready to implement workflows, though it presumes familiarity with structural methods and software.\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDoes the book include step-by-step protocols?\u003c\/strong\u003e\u003cbr\u003eYes. The volume is organized around practical, protocol-style chapters designed for implementation in computational and experimental workflows.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhich docking tools are discussed?\u003c\/strong\u003e\u003cbr\u003eChapters cover AnchorDock, ATTRACT, HADDOCK and FlexPepDock for blind and flexible peptide docking approaches.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIs this suitable for beginners?\u003c\/strong\u003e\u003cbr\u003eNot ideal for complete beginners; the text assumes prior knowledge of protein structure and computational methods.\u003c\/p\u003e","brand":"Ora Schueler-Furman, Nir London","offers":[{"title":"Default Title","offer_id":48751790719195,"sku":"1493983024","price":96.63,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0724\/1043\/1707\/files\/61_gH893qoL._SL1180.jpg?v=1778800955","url":"https:\/\/gearmusthave.com\/products\/modeling-peptide-protein-interactions-methods-and-protocols","provider":"GearMustHave","version":"1.0","type":"link"}