{"product_id":"platinum-based-drugs-in-cancer-therapy-comprehensive-oncology-text","title":"Platinum-Based Drugs in Cancer Therapy - Comprehensive Oncology Text","description":"\u003cp\u003eIn this review of Platinum-Based Drugs in Cancer Therapy, the bottom line is clear: this is an advanced, interdisciplinary survey best suited to oncology researchers and clinicians who need a focused, mechanistic treatment of platinum anticancer agents. The book compiles contributions from international experts and offers the most useful single-volume discussion of platinum drug chemistry, DNA interactions, transport into tumor cells, and emergent agents, making it a valuable reference rather than a basic textbook for students.\u003c\/p\u003e\n\u003ch2\u003eKey Features\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eComprehensive coverage:\u003c\/strong\u003e Reviews chemistry, molecular mechanisms, and clinical use of platinum drugs in one focused volume for rapid reference.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExpert contributors:\u003c\/strong\u003e Leading international specialists provide authoritative perspectives across chemistry, biology, and clinical oncology.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular detail:\u003c\/strong\u003e Examines platinum drug interactions with DNA, including mismatch repair and replicative bypass, to clarify mechanism-based resistance and response.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTransport and apoptosis:\u003c\/strong\u003e Discusses the transport of platinum agents into tumor cells and the role of apoptosis in therapeutic outcomes, informing translational research.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFuture agents considered:\u003c\/strong\u003e Evaluates emergent platinum drugs such as orally active compounds, ZD0473, and the polynuclear BBR3464 to outline future therapeutic prospects.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWho It's For\u003c\/h2\u003e\n\u003cp\u003eThe primary audience is oncology specialists, medicinal chemists, and cancer therapeutics researchers who need an in-depth, mechanistic review of platinum anticancer agents and their clinical applications. It is particularly useful for clinicians and investigators working on drug resistance, DNA repair pathways, and novel platinum compounds.\u003c\/p\u003e\n\u003cp\u003eThose seeking an introductory textbook or a clinical guide to general cancer care should look elsewhere; the book assumes familiarity with molecular biology and inorganic chemistry and is written as a specialist reference rather than a primer for nonexperts.\u003c\/p\u003e\n\u003ch2\u003ePros \u0026amp; Cons\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003ePros\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAuthoritative interdisciplinary chapters that synthesize chemistry and clinical perspectives for holistic understanding.\u003c\/li\u003e\n\u003cli\u003eDetailed discussion of DNA interactions and cellular transport mechanisms that informs research into resistance and therapeutic improvement.\u003c\/li\u003e\n\u003cli\u003eCoverage of emergent compounds like ZD0473 and BBR3464 gives readers insight into future drug development directions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eCons\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eThe material is specialist and dense, which limits accessibility for readers without a strong background in molecular oncology or chemistry.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003eTitle\u003c\/td\u003e\n\u003ctd\u003ePlatinum-Based Drugs in Cancer Therapy\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSeries\u003c\/td\u003e\n\u003ctd\u003eCancer Drug Discovery and Development\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAuthors \/ Editors\u003c\/td\u003e\n\u003ctd\u003eLloyd R. Kelland, Nicholas P. Farrell\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eScope\u003c\/td\u003e\n\u003ctd\u003eChemistry, molecular interactions, transport, apoptosis, and future agents\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFocus\u003c\/td\u003e\n\u003ctd\u003ePlatinum anticancer drugs and therapeutic prospects\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAudience\u003c\/td\u003e\n\u003ctd\u003eOncology researchers, medicinal chemists, cancer therapeutics specialists\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003ch2\u003eOur Verdict\u003c\/h2\u003e\n\u003cp\u003ePlatinum-Based Drugs in Cancer Therapy is a strong, specialist reference that pulls together chemistry, cellular biology, and clinical perspectives on platinum agents. Researchers and clinicians focused on mechanism, resistance, and novel platinum compounds will find it excellent value; readers seeking an introductory or broad clinical text should consider a different title.\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDoes this book cover new platinum compounds?\u003c\/strong\u003e\u003cbr\u003eYes. The text specifically discusses emergent agents including orally active compounds, ZD0473, and the polynuclear BBR3464.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIs the book suitable for general clinical practice?\u003c\/strong\u003e\u003cbr\u003eThe volume is specialist in tone and best suited to researchers and oncology clinicians rather than general practitioners seeking a broad clinical manual.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes it address mechanisms of resistance?\u003c\/strong\u003e\u003cbr\u003eYes. It examines DNA mismatch repair, replicative bypass, and transport mechanisms that underpin resistance and response to platinum drugs.\u003c\/p\u003e","brand":"Lloyd R. Kelland, Nicholas P. Farrell","offers":[{"title":"Default Title","offer_id":48741279105243,"sku":"1617370916","price":119.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0724\/1043\/1707\/files\/61TV2vczQUL._SL1253.jpg?v=1778995124","url":"https:\/\/gearmusthave.com\/products\/platinum-based-drugs-in-cancer-therapy-comprehensive-oncology-text","provider":"GearMustHave","version":"1.0","type":"link"}