Brooks Mens Glycerin 22 Neutral Running Shoe - Plush Cushioning foot

In this review of the Brooks Mens Glycerin 22 Neutral Running Shoe the bottom line is simple: this is a plush, neutral road trainer for runners and walkers who prioritize soft cushioning and smooth transitions. The standout reason to buy is the DNA Tuned midsole that blends larger heel cells with smaller forefoot cells to deliver a soft landing and an energetic toe-off. It also carries PDAC A5500 diabetic certification and the APMA Seal of Acceptance, making it an appealing option for anyone seeking extra comfort and foot health reassurance.

Key Features

• DNA Tuned Cushion: The midsole integrates dual-size cells so the heel feels soft and cushioned while the forefoot stays responsive for push-offs.
• Neutral Support: Designed as a neutral shoe, it offers the maximum amount of cushioning without added stability posts, suitable for natural foot motion.
• Accommodating Fit: A double jacquard knit upper delivers flexibility and breathability while conforming to the foot for daily comfort.
• Smooth Transitions: A broad platform and tuned heel-to-toe geometry stabilize the foot and smooth heel-to-toe movement during runs or walks.
• Certified Comfort: PDAC A5500 diabetic certification and the APMA Seal of Acceptance signal design choices intended to reduce pressure points and support foot health.

Who It's For

The Glycerin 22 is best for neutral road runners, walkers, and gym-goers who want maximum cushioning and a plush ride for daily miles or long walks. It works well for people who value a soft heel strike and a responsive forefoot during tempo changes or casual runs.

Runners who need strong corrective support or firms who prefer a very narrow race-oriented fit should look elsewhere; if you require firm motion control or minimalist responsiveness, the Glycerin 22's plush, forgiving profile will feel too soft.

Pros & Cons

Pros

• Excellent cushioning that reduces impact on long runs and long walks.
• DNA Tuned midsole provides a balanced blend of plush landings and lively toe-offs.
• Accommodating knit upper gives breathable comfort and adapts to foot shape.
• Certified PDAC A5500 and APMA Seal add confidence for foot health and comfort.

Cons

• Fit reports vary; some users find the shoe narrow while others find it roomy, so trying on or checking return options is advised.

Specifications

Model	Glycerin 22
Support type	Neutral
Midsole technology	DNA Tuned dual-size cell cushioning
Upper	Double jacquard knit, breathable and flexible
Certifications	PDAC A5500 Diabetic; APMA Seal of Acceptance
Predecessor	Glycerin 21

Our Verdict

The Brooks Glycerin 22 is a strong pick for runners and walkers who want maximum cushioning with a smooth ride and foot-health credentials. Its DNA Tuned cushioning and accommodating knit upper make it good value for everyday training, recovery runs, and long walks, provided you confirm the fit for your foot width before committing.

Frequently Asked Questions

Are these shoes good for long walks?
Yes. The plush cushioning and stable platform make them comfortable for long walks and extended wear.

Do they offer support for overpronation?
No. The Glycerin 22 is a neutral shoe; those needing added support should consider a stability model instead.

Should I size up for a wider fit?
Fit varies by foot shape; some users find them narrow and others wide, so try your usual running size and use return options if width is a concern.