Brooks Mens Glycerin 22 Neutral Running Shoe - Plush Cushioning has

In this review the Brooks Mens Glycerin 22 is presented as a neutral running shoe built for runners and walkers who want maximum cushioning without extra stability features. The biggest reason to consider these shoes is the DNA Tuned midsole, which blends larger heel cells with smaller forefoot cells for soft landings and responsive toe-offs, delivering a pillowy ride that still moves you forward. This model also carries both PDAC A5500 diabetic certification and the APMA Seal of Acceptance, making it a strong choice for anyone prioritizing cushioning and foot health.

Key Features

• DNA Tuned Cushion: Larger midsole cells in the heel provide plush landings while smaller forefoot cells promote energetic toe-offs for smoother transitions.
• Neutral Support: The shoe provides neutral support with maximum cushioning, suitable for road runs, cross training, and daily walking without added corrective structure.
• Accommodating Fit: A double jacquard knit upper offers flexibility and breathability while conforming to the foot for comfortable wear.
• Stable Platform: A broad midsole platform stabilizes the foot and works with the tuned heel and forefoot to smooth heel-to-toe movement.
• Certified Comfort: PDAC A5500 diabetic certification and APMA Seal of Acceptance indicate design attention to foot health and protective cushioning.

Who It's For

The Glycerin 22 suits runners who want the softest ride Brooks offers in a neutral shoe, plus walkers and people on their feet all day who value thick, consistent cushioning and certified foot health features. It is especially useful for road running, gym work, casual cross training, and everyday wear where comfort and padding are priorities.

Those who need strong motion control, a built-in support guide, or a very narrow race shoe should look elsewhere; Brooks Glycerin GTS 22 or more stability-focused models add support for overpronation, and racers will prefer lighter, lower-profile trainers for speedwork.

Pros & Cons

Pros

• Exceptional cushioning from DNA Tuned midsole for soft landings and lively toe-offs.
• Comfortable, breathable double jacquard knit upper that accommodates foot movement.
• Broad platform offers stable, smooth heel-to-toe transitions for everyday use.
• Certifications for diabetic footwear and APMA Seal reflect attention to foot health.

Cons

• Fit opinions vary; some wearers with wider feet find them perfect while others report a narrower feel, so sizing may be inconsistent.
• Not designed for runners seeking maximal support for overpronation or a racer-style low-profile shoe.

Specifications

Our Verdict

The Brooks Mens Glycerin 22 is an excellent choice for runners and walkers who prioritize plush cushioning and smooth transitions without added stability features. Its DNA Tuned midsole and broad platform deliver comfortable landings and responsive toe-offs, and the diabetic and APMA certifications add confidence for foot health. It represents good value for anyone wanting maximum daily comfort, though those needing extra support should consider stability variants.

Frequently Asked Questions

Are these shoes good for walking?
Yes, customers consistently note the Glycerin 22 is fantastic for walking and everyday use thanks to its cushioning and stable platform.

Do they run true to size?
Fit reports vary: some find true-to-size or perfect for wider feet, while others experience a narrower fit, so trying them on or checking return options is recommended.

Is this shoe suitable for diabetic feet?
Yes, the Glycerin 22 is PDAC A5500 certified and has the APMA Seal of Acceptance, indicating it meets criteria for protective cushioning and foot health.