Brooks Mens Glycerin 22 Neutral Running Shoe - Plush Cushioning same

In this review the Brooks Mens Glycerin 22 Neutral Running Shoe earns its place for runners and walkers who prioritize maximum cushioning and smooth transitions. The single biggest reason to consider the Glycerin 22 is its DNA Tuned midsole, which blends larger heel cells with smaller forefoot cells to deliver soft landings and responsive toe-offs, while also offering an accommodating knit upper and neutral support for everyday road miles and long walks. It is notable as a certified PDAC A5500 diabetic shoe and carries the APMA Seal of Acceptance, reinforcing its focus on comfort and foot health.

Key Features

• DNA Tuned Cushion: The midsole pairs larger cells in the heel with smaller forefoot cells to create plush landings and energetic toe-offs for smoother strides.
• Neutral Support: Designed as a neutral shoe, it provides maximal cushioning without added corrective support, making it versatile for road running and cross training.
• Accommodating Fit: The double jacquard knit upper stretches to fit a variety of foot shapes while maintaining breathability and durability during longer use.
• Smooth Transitions: A broad platform and tuned heel-to-forefoot geometry help stabilize the foot and reduce abrupt changes through the gait cycle.
• Health-Focused Certification: Certified as a PDAC A5500 diabetic shoe and awarded the APMA Seal of Acceptance for features that promote foot health and comfort.

Who It's For

The Glycerin 22 is best for runners and walkers who want maximum cushioning and a neutral ride, especially those with heel sensitivity or who value a plush feel for daily training and long walks. It suits people with wider feet or those who appreciate an accommodating knit upper and stable platform for comfortable, long-distance use.

It is less appropriate for runners who need firm responsiveness for race paces or those requiring strong corrective support; shoppers seeking overt stability should consider a guidance-support model rather than this neutral cushioning shoe.

Pros & Cons

Pros

• Exceptional cushioning in the heel and forefoot for comfortable long walks and runs.
• Accommodating, breathable knit upper that fits wider feet well and reduces pressure points.
• Smooth, stable transitions aided by a broad platform and tuned midsole geometry.
• Recognized health credentials with PDAC A5500 certification and the APMA Seal of Acceptance.

Cons

• Neutral setup may not offer enough corrective support for runners who overpronate and need motion control features.
• Some shoppers report mixed opinions on value compared with alternatives, though quality and comfort are consistently praised.

Specifications

Model	Glycerin 22
Support	Neutral
Cushion Technology	DNA Tuned midsole with dual-size cells
Upper	Double jacquard knit for flexibility and breathability
Certifications	PDAC A5500 diabetic shoe; APMA Seal of Acceptance
Predecessor	Glycerin 21

Our Verdict

The Brooks Mens Glycerin 22 is a strong choice for anyone seeking plush cushioning, an accommodating fit, and smooth heel-to-toe transitions for walking and daily training. Its diabetic-friendly certification and APMA acceptance make it especially appealing to those prioritizing foot health, while neutral runners who want maximum comfort will find good value in the updated midsole design.

Frequently Asked Questions

Are these shoes good for wide feet?
Yes, the double jacquard knit upper provides an accommodating fit that many customers report works well for wider feet.

Do they offer stability for overpronation?
No, the Glycerin 22 is a neutral shoe; runners needing corrective support should look at models with added guidance or stability features.

Is the cushioning firm or soft?
The cushioning leans toward the plush side, with larger heel cells for soft landings and smaller forefoot cells for responsive toe-offs.