Brooks Mens Glycerin 22 Neutral Running Shoe - Plush (Style 8QLY)

In this review the Brooks Mens Glycerin 22 stands out as a neutral running shoe built for runners and walkers who prioritize plush cushioning and smooth transitions. The single biggest reason to buy is its updated DNA Tuned midsole, which blends larger heel cells for soft landings with smaller forefoot cells for energetic toe-offs, delivering a reliably cushioned yet responsive ride for road miles or long walks.

Key Features

• Neutral support: Provides a neutral platform with the maximum amount of cushioning, suitable for road running, cross training, and everyday wear.
• DNA Tuned cushion: The midsole integrates dual-size cells so the heel feels plush while the forefoot remains springy for better toe-offs.
• Accommodating fit: The double jacquard knit upper offers a flexible, breathable fit that adapts well to wider foot shapes without feeling tight.
• Smooth transitions: A broad platform and tuned heel/forefoot geometry stabilizes the foot and smooths heel-to-toe movement.
• Medical endorsements: Certified as a PDAC A5500 diabetic shoe and awarded the APMA Seal of Acceptance for foot health considerations.

Who It's For

The Glycerin 22 is best for neutral runners and walkers who want maximum cushioning without added corrective support, and for anyone with wider feet seeking an accommodating knit upper. It suits daily road runs, long walks, gym sessions, and crossover use where comfort and impact protection are priorities.

Runners who need significant motion control or custom orthotics support should look at stability models such as the Glycerin GTS 22 or other stability shoes, while minimalists or racers who prefer a very firm, low-stack feel will find the Glycerin 22 too cushioned for tempo workouts.

Pros & Cons

Pros

• Exceptional heel cushioning with softer landings thanks to larger midsole cells.
• Comfortable, breathable double jacquard knit upper that accommodates wider feet.
• Smooth, stable transitions from heel to toe on road surfaces.
• APMA Seal of Acceptance and PDAC A5500 diabetic certification add confidence for foot health.

Cons

• Maximum cushioning makes the shoe feel bulky for runners who prefer a firmer, more responsive racing shoe.
• Value perceptions vary among customers; some may find the price higher than expected for their needs.

Specifications

Model	Glycerin 22
Support	Neutral
Midsole tech	DNA Tuned dual-size cells
Upper	Double jacquard knit, breathable
Certifications	PDAC A5500 diabetic shoe; APMA Seal of Acceptance
Predecessor	Glycerin 21

Our Verdict

The Brooks Mens Glycerin 22 is a strong choice for runners and walkers who want maximum cushioning, an accommodating knit fit, and a smooth ride. Its DNA Tuned midsole and broad platform make it particularly valuable for long walks, daily runs, and anyone seeking extra impact protection while maintaining responsive toe-offs.

Frequently Asked Questions

Are these shoes good for wide feet?
The double jacquard knit upper provides a flexible, accommodating fit that many users with wider feet find comfortable.

Is the Glycerin 22 a stability shoe?
No, the Glycerin 22 is a neutral shoe; choose the Glycerin GTS 22 for added support and stability.

Can I use these for long walks?
Yes, customers report excellent cushioning and heel comfort for extended walks, making them well suited to multi-mile outings.