Brooks Mens Glycerin 22 Neutral Running Shoe - Plush (Style J9JC)
Brooks Mens Glycerin 22 Neutral Running Shoe - Plush (Style J9JC)
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In this review of the Brooks Mens Glycerin 22 Neutral Running Shoe the bottom line is simple: this is a plush, neutral road shoe built for runners and walkers who prioritize maximum cushioning and smooth transitions. The standout reason to consider the Glycerin 22 is its DNA Tuned midsole, which blends larger heel cells and smaller forefoot cells to deliver soft landings and responsive toe-offs while maintaining a broad, stable platform. It is also notable for medical endorsements, holding PDAC A5500 diabetic shoe certification and the APMA Seal of Acceptance, which underlines its accommodating fit and foot health credentials.
Key Features
- DNA Tuned Cushion: Larger midsole cells in the heel provide plush, forgiving landings while smaller forefoot cells encourage a responsive toe-off for smoother stride transitions.
- Neutral Support: Designed as a neutral shoe that offers the maximum amount of cushioning, suitable for road running, cross training, and long walks.
- Accommodating Fit: The double jacquard knit upper stretches where needed to fit wider feet comfortably while maintaining breathable durability.
- Smooth Transitions: A broad platform and tuned heel-to-toe geometry stabilize the foot and reduce abrupt motion during gait changes.
- Medical Certifications: Certified PDAC A5500 as a diabetic shoe and awarded the APMA Seal of Acceptance, supporting foot health for those who need extra care.
Who It's For
The Glycerin 22 is best for neutral runners and walkers who want plush cushioning for daily miles, long training runs, or extended walks where heel cushioning and comfort matter most. It serves athletes who have flat feet seeking supportive cushioning rather than corrective stability, and those with wider feet will appreciate the accommodating knit upper.
Runners who need firm responsiveness, minimal cushioning, or strong motion control should look elsewhere, as the Glycerin 22 prioritizes softness and a cushioned ride over maximal responsiveness or aggressive stability features found in support-specific models.
Pros & Cons
Pros
- Exceptional heel cushioning and overall plush ride thanks to the DNA Tuned midsole.
- Accommodating, breathable double jacquard knit upper that handles wider feet well.
- Broad platform and tuned geometry deliver smooth, stable heel-to-toe transitions.
- PDAC A5500 diabetic shoe certification and APMA Seal of Acceptance for foot-health considerations.
Cons
- Heaviness and maximal cushioning may reduce energetic responsiveness for tempo runs.
- Value perceptions vary among customers; some buyers find the price high relative to features.
Specifications
| Model | Glycerin 22 |
| Support | Neutral |
| Midsole Technology | DNA Tuned with dual-size cells |
| Upper | Double jacquard knit, breathable and accommodating |
| Certifications | PDAC A5500 diabetic shoe, APMA Seal of Acceptance |
| Best Uses | Road running, walking, cross training, gym |
Our Verdict
The Brooks Mens Glycerin 22 is a top pick for runners and walkers who want the softest possible ride and an accommodating fit without sacrificing stability during transitions. Its medical certifications add confidence for those concerned with foot health, making it a strong value for anyone prioritizing cushioning and comfort over race-day responsiveness.
Frequently Asked Questions
Are these shoes good for wide feet?
The double jacquard knit upper is designed to accommodate wider feet and customers report a comfortable fit for broad foot shapes.
Can I use the Glycerin 22 for daily running and long walks?
Yes, the maximum cushioning and stable platform make it well suited for daily miles and long 6-mile-plus walks.
Is this shoe suitable for people with diabetic foot concerns?
Yes, it is certified PDAC A5500 and carries the APMA Seal of Acceptance, indicating it meets standards for diabetic and foot-health friendly footwear.
Editor's Take
The Glycerin 22 delivers plush cushioning, smooth transitions, and an accommodating fit, making it ideal for neutral runners and walkers who prioritize comfort and foot health.

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