Brooks Mens Glycerin 22 Neutral Running Shoe - Plush (Style SHTG)
Brooks Mens Glycerin 22 Neutral Running Shoe - Plush (Style SHTG)
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In this review the Brooks Mens Glycerin 22 stands out as a go-to neutral trainer for runners and walkers who prioritize soft, consistent cushioning. The biggest reason to buy is its updated DNA Tuned cushion, which blends larger heel cells for plush landings with smaller forefoot cells for responsive toe-offs, producing notably smooth transitions on roads and sidewalks. The shoe also carries the APMA Seal of Acceptance and is PDAC A5500 certified, making it a strong choice for those who need an accommodating, foot-friendly ride.
Key Features
- Neutral support: Designed for runners who need neutral alignment with the maximum amount of cushioning for daily miles or long walks.
- DNA Tuned cushion: Larger heel cells create soft landings while smaller forefoot cells encourage energetic toe-offs for a balanced ride.
- Accommodating fit: The double jacquard knit upper flexes and breathes while providing a roomy feel that works well for wider feet.
- Smooth, stable transitions: A broad platform and tuned heel-to-toe geometry reduce wobble and make heel-to-toe motion feel seamless.
- Medical endorsements: PDAC A5500 diabetic certification and the APMA Seal of Acceptance indicate attention to foot health and comfort.
Who It's For
The Glycerin 22 is best for neutral runners and regular walkers who want the maximum cushioning without added stability features, and for people with flat or wider feet who need an accommodating toe box and reliable heel cushioning. It also suits gym users and cross trainers who prefer extra plush underfoot feel during low-impact sessions.
Runners seeking a firm, performance race shoe or those who require strong corrective support should look elsewhere; if you need motion control or a stability frame, the Glycerin GTS 22 or a dedicated stability model will be a better match.
Pros & Cons
Pros
- Excellent heel and overall cushioning that feels supportive on long walks and runs.
- Roomy, breathable double jacquard knit upper suits wider feet and improves comfort.
- Stable broad platform and tuned midsole produce smooth heel-to-toe transitions.
- Recognized foot-health credentials with PDAC A5500 and APMA Seal.
Cons
- Maximum cushioning adds weight and may feel bulky for fast tempo runs.
- Some buyers have mixed opinions on value compared with previous models.
Specifications
| Model | Glycerin 22 |
| Support type | Neutral |
| Cushioning system | DNA Tuned midsole |
| Upper | Double jacquard knit |
| Platform | Broad platform for stability |
| Certifications | PDAC A5500 diabetic approved, APMA Seal of Acceptance |
Our Verdict
The Brooks Mens Glycerin 22 is a strong choice for runners and walkers who want maximum, well-engineered cushioning and an accommodating fit. Its DNA Tuned midsole and broad platform deliver smooth transitions and dependable comfort, making it worthwhile for everyday training and long walks, especially for wider or flat feet.
Frequently Asked Questions
Are these shoes good for wide feet?
Yes, the double jacquard knit upper provides a flexible, more accommodating fit that suits wider feet.
Is the Glycerin 22 suitable for long walks?
Yes, customers report excellent heel cushioning and comfort for multi-mile walks and daily use.
How does this differ from the Glycerin 21?
The Glycerin 22 updates the midsole tuning and upper knit for improved transitions and a more flexible, breathable fit.
Editor's Take
The Glycerin 22 is ideal for runners and walkers who want maximum, well-engineered cushioning and an accommodating fit; its DNA Tuned midsole and broad platform deliver smooth transitions and lasting comfort.

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