Brooks Mens Glycerin 22 Neutral Running Shoe - Plush (Style WZQG)

In this review of the Brooks Mens Glycerin 22 Neutral Running Shoe the bottom line is simple: this is a top pick for runners and walkers who want maximum cushioning with a smooth, stable ride. The shoe stands out because of its DNA Tuned midsole construction that blends larger heel cells and smaller forefoot cells to deliver soft landings and responsive toe-offs, making it a comfortable choice for long walks, road runs, or daily gym sessions. The Glycerin 22 is also certified as a PDAC A5500 diabetic shoe and carries the APMA Seal of Acceptance, which adds confidence for buyers prioritizing foot health.

Key Features

• DNA Tuned Cushion: Larger midsole cells in the heel offer plush cushioning for softer landings while smaller forefoot cells promote responsive toe-offs for a lively stride.
• Neutral Support: Designed for neutral runners, it provides maximum cushioning without added pronation control, suitable for road running and cross training.
• Accommodating Fit: The double jacquard knit upper gives a flexible, breathable fit that adapts to wider feet and long wear.
• Smooth Transitions: A broad platform with a tuned heel and forefoot delivers stable, heel-to-toe transitions that reduce harsh impacts.
• Health Certifications: Certified PDAC A5500 and APMA accepted, offering reassurance for users who need footwear mindful of diabetic or podiatric concerns.

Who It's For

The Glycerin 22 is best suited to neutral runners and active walkers who value maximum cushioning and a forgiving ride. It works well for longer road runs, daily gym sessions, and multi-mile walks thanks to the plush heel and accommodating knit upper that comfortably fits wider feet.

Runners who need strong stability or corrective support should look at models with guidance or support in the name, such as a GTS option, since the Glycerin 22 is focused on neutral cushioning rather than motion control. Those seeking a minimalist or very lightweight racing shoe may prefer a different, less-cushioned model.

Pros & Cons

Pros

• Exceptional heel cushioning that many customers find comfortable for walking and running.
• Broad, stable platform and tuned transitions for a smooth stride.
• Accommodating knit upper that suits wider feet and offers good breathability.
• Health-minded certifications like PDAC A5500 and APMA Seal of Acceptance.

Cons

• Maximal cushioning adds weight compared with lighter racing shoes, which some runners may not prefer.
• Neutral setup is not ideal for those requiring strong pronation control or corrective support.

Specifications

Our Verdict

The Brooks Mens Glycerin 22 is a strong choice for anyone who prioritizes cushioning and comfort over minimal weight. It offers a plush, stable ride with an accommodating fit that benefits walkers, neutral runners, and those with wider feet, and its PDAC and APMA certifications add practical value for foot health. Choose this shoe when smooth transitions and long-wear comfort matter most.

Frequently Asked Questions

Are these shoes good for wide feet?
Yes, the double jacquard knit upper is designed to be accommodating and many customers report a comfortable fit for wider feet.

Can I use the Glycerin 22 for long walks?
Yes, the plush heel cushioning and stable platform make it well suited for multi-mile walks and daily walking use.

Is this shoe suitable for people with diabetes?
Yes, it is certified PDAC A5500 and has the APMA Seal of Acceptance, indicating it meets standards useful for diabetic foot care.