Brooks Mens Glycerin 22 Neutral Running Shoe - Smooth Everyday Cushion
Brooks Mens Glycerin 22 Neutral Running Shoe - Smooth Everyday Cushion
Price subject to change. Tap below for current.
Couldn't load pickup availability
In this review of the Brooks Mens Glycerin 22 Neutral Running Shoe the bottom line is simple: this shoe is for runners and walkers who want consistently soft, reliable cushioning on daily miles. The biggest reason to buy is the updated nitrogen-infused DNA LOFT v3 midsole, which adds an extra 1mm in the heel and 3mm in the forefoot compared with the predecessor for a noticeably plusher ride. Reviewers praising comfort and walking ability line up with the product's certifications, making it a solid pick for long wear and those needing supportive neutral cushioning.
Key Features
- Premium cushioning: Nitrogen-infused DNA LOFT v3 in the heel and forefoot delivers lightweight softness that keeps feet comfortable over long runs and walks.
- Smooth transitions: Precise flex grooves in the midsole promote a natural toe-off and help maintain momentum during varied paces.
- Breathable upper: Double jacquard air mesh offers airflow and a snug, adaptive fit that reduces hot spots during repeated use.
- Durable outsole: A rubber compound with recycled silica balances durability and responsive rebound for reliable traction on road surfaces.
- Medical endorsements: Certified PDAC A5500 diabetic shoe and APMA Seal of Acceptance signal attention to support and comfort for sensitive feet.
- Carbon neutral: The shoe is produced as a certified carbon neutral product, reducing its environmental footprint.
Who It's For
The Brooks Mens Glycerin 22 is best for everyday runners, walkers, gym-goers and travelers who prioritize plush cushioning and a smooth ride. It suits neutral runners and people with flat feet who appreciated the added heel cushioning and supportive feel reported by customers.
Those who want a minimalist, highly responsive race shoe or a very firm, performance-focused trainer should look elsewhere, as this model emphasizes softness and comfort over a stiff, speed-oriented platform.
Pros & Cons
Pros
- Excellent cushioning and heel comfort, praised by many customers for walking and running.
- Breathable double jacquard mesh upper that adapts to foot movement and reduces heat buildup.
- Stable, smooth transitions from the precise flex grooves for a natural stride.
- Recognized support with PDAC and APMA acceptance and a certified carbon neutral manufacturing claim.
Cons
- Some customers find the price high compared with other everyday trainers, so value opinions are mixed.
- The extra plush midsole may feel too soft for runners seeking a firmer, more responsive ride.
Specifications
| Model | Glycerin 22 (successor to Ghost 16) |
| Cushioning | Nitrogen-infused DNA LOFT v3 (extra 1mm heel, 3mm forefoot) |
| Support | Neutral support with smooth transitions from flex grooves |
| Upper | Double jacquard air mesh with kick-back collar |
| Outsole | Rubber compound with recycled silica for durability and rebound |
| Certifications | PDAC A5500 diabetic shoe, APMA Seal of Acceptance, certified carbon neutral |
Our Verdict
The Brooks Mens Glycerin 22 is a strong choice for anyone seeking plush, trustworthy cushioning for daily runs, long walks, or all-day wear. Its combination of DNA LOFT v3 comfort, smooth midsole transitions, and supportive upper makes it worth the investment for those prioritizing foot comfort and durability, though shoppers wanting a firmer racing feel should consider other options.
Frequently Asked Questions
Are these shoes good for walking?
Yes, customers consistently report excellent walking ability and heel cushioning, making them well suited to long periods on foot.
Do they fit wide feet?
The adaptive mesh upper and roomy design have been noted as suitable for wider feet, with many reviewers finding the fit comfortable.
Are they appropriate for flat feet?
They offer neutral support with good cushioning and have been reported to provide sufficient support for many people with flat feet, though personalized needs vary.
Editor's Take
The Brooks Mens Glycerin 22 delivers plush, consistent cushioning and smooth transitions, making it a smart choice for everyday runners and walkers who prioritize comfort and support.

Recently viewed
Recently viewed products will appear here as customers browse the store.