Brooks Mens Glycerin GTS 22 Supportive Running Shoe (Style QHTY)

Our review of the Brooks Mens Glycerin GTS 22 finds it best for runners and active men who need plush cushioning plus reliable stability. The single biggest reason to consider these shoes is the combination of Brooks' DNA Tuned cushion with GuideRails support, which creates soft landings in the heel and responsive toe-offs while keeping excess motion under control. The Glycerin GTS 22 is also a certified PDAC A5500 diabetic shoe, so it can serve buyers who need medically recognized accommodation along with everyday running performance.

Key Features

• GuideRails support: Keeps excess motion in check so the foot stays aligned through heel-to-toe transitions for steadier runs and walks.
• DNA Tuned cushion: Uses larger midsole cells in the heel for soft landings and smaller cells in the forefoot for more energetic toe-offs, balancing comfort and responsiveness.
• Accommodating fit: A double jacquard knit upper stretches and breathes to reduce hotspots while providing durable coverage over long wear.
• Smooth transitions: A broad platform with a tuned heel and forefoot encourages stable, fluid movement from strike to push-off.
• PDAC A5500 diabetic certification: Offers an added level of fit and internal volume suitable for users who require diabetic-friendly footwear.

Who It's For

The Glycerin GTS 22 is aimed at road runners, gym users and anyone who spends long periods on their feet and values cushioning with supportive control. Runners who experience mild overpronation or who want a steadier platform without losing plush comfort will find the GuideRails and DNA Tuned midsole a good match.

Those who prefer an exceptionally wide toe box or require a very narrow race fit should look elsewhere, as some users report the toe area can feel a bit narrow. Also, runners seeking a minimal, barefoot-style shoe will not appreciate the substantial cushioning and support in this model.

Pros & Cons

Pros

• Exceptional cushioning that reduces impact-related discomfort for long days and recovery runs.
• GuideRails system provides tangible stabilization for runners with excess motion concerns.
• Double jacquard knit upper balances breathability and a comfortable, accommodating fit.
• Certified PDAC A5500 status supports diabetic-friendly use cases.

Cons

• Some testers and customers find the forefoot a little narrow, which may not suit wide-footed buyers.

Specifications

Model	Glycerin GTS 22
Support system	GuideRails holistic support
Midsole technology	DNA Tuned with dual-size cells
Upper	Double jacquard knit for flexible, breathable fit
Use case	Road running, cross training, gym
Certification	PDAC A5500 diabetic shoe

Our Verdict

The Brooks Glycerin GTS 22 is a strong choice for runners and active men who want plush cushioning without sacrificing stability; its DNA Tuned midsole and GuideRails support deliver comfortable landings and controlled motion, making it good value for everyday training and people who need diabetic-approved footwear.

Frequently Asked Questions

Are these shoes good for overpronation?
Yes, the GuideRails support is designed to limit excess motion and help stabilize moderate overpronation during runs.

Do they run true to size?
Many users report a generally true fit but some find the forefoot narrow, so those with wide toes should consider trying them on or ordering a wider size if available.

Can I use them for gym workouts and everyday wear?
Yes, the broad platform and comfortable cushioning make them suitable for road running, cross training, gym sessions and extended daily wear.