Brooks Womens Glycerin 22 Neutral Running Shoe for Women - Luxurious

In this review the Brooks Womens Glycerin 22 is presented as a top choice for runners and gym-goers who prioritize soft, reliable cushioning without extra stability features. The single biggest reason to buy is its DNA Tuned midsole that balances plush landings with energetic toe-offs, delivering a smooth ride for neutral-strike runners and those who want maximum cushioning. Our review finds the shoe works well on road runs, cross training and everyday gym sessions while meeting medical comfort standards prized by diabetic users.

Key Features

• Certified Diabetic Comfort: This model is a certified PDAC A5500 diabetic shoe and carries the APMA Seal of Acceptance, offering reassurance for users needing foot-friendly footwear.
• DNA Tuned Cushion: The dual-size midsole cells provide softer heel landings and a responsive forefoot for smoother transitions from heel to toe.
• Neutral Support: Designed as a neutral shoe, it provides the maximum amount of cushioning without added motion control so it suits neutral-strike runners.
• Accommodating Fit: The double jacquard knit upper stretches for a flexible, breathable fit while remaining durable through regular use.
• Stable Platform: A broad midsole platform and tuned heel improve stability and help create steady, smooth transitions during runs.

Who It's For

The Glycerin 22 is aimed at women who want luxurious cushioning for road running, gym workouts, or daily wear where comfort is the priority. Neutral runners who prefer a plush ride and responsive toe-offs will appreciate the DNA Tuned midsole and broad platform for stable, comfortable reps and miles.

Runners who need added motion control or pronounced arch support should consider a stability model instead, such as the Brooks Glycerin GTS 22 which adds guidance features. Also, trail runners or those needing aggressive outsole bite should look for a shoe built specifically for off-road terrain.

Pros & Cons

Pros

• Exceptional cushioning that many customers describe as plush and comfortable.
• Accommodating toe box and padded heel that improve fit and reduce hotspots.
• APMA Seal and PDAC A5500 certification give confidence for users with foot health concerns.
• Breathable, flexible upper that balances durability with comfort.

Cons

• Higher price is a concern for some buyers who question value for money.
• Neutral support means it is not the best choice for runners who require strong pronation control.

Specifications

Our Verdict

The Brooks Womens Glycerin 22 is a strong choice for women seeking maximum cushioning and a smooth, stable ride on roads and in the gym. Its DNA Tuned midsole and accommodating knit upper make it comfortable for long runs and everyday wear, and the medical certifications add extra value for foot health. Those needing motion control should choose a stability variant instead.

Frequently Asked Questions

Is the Glycerin 22 good for long runs?
Yes, the plush DNA Tuned cushioning and stable platform make it well suited for long road runs for neutral runners.

Does this shoe offer support for diabetic feet?
Yes, it is certified PDAC A5500 and has the APMA Seal of Acceptance for foot-friendly design.

Should I pick this if I overpronate?
If you overpronate, consider the Glycerin GTS 22 or another stability shoe, since the Glycerin 22 is a neutral model.