Brooks Womens Glycerin 22 Neutral Running Shoe - Plush Cushioning

In this review of the Brooks Womens Glycerin 22 Neutral Running Shoe the bottom line is simple: runners and active women who want the maximum in everyday cushioning will appreciate these shoes. The Glycerin 22 is built around Brooks' latest DNA Tuned midsole that blends larger heel cells for soft landings with smaller forefoot cells for responsive toe-offs, so the single biggest reason to buy is the combination of luxurious comfort and smoother transitions during runs or cross training.

Key Features

• DNA Tuned Cushion: Dual-size midsole cells create a plush heel landing and a responsive forefoot for energetic toe-offs on the road.
• Neutral Support: Provides neutral guidance with maximum cushioning, making it suitable for road running and general training without corrective structure.
• Accommodating Fit: The double jacquard knit upper delivers flexible stretch and breathability while holding its shape for comfortable long wear.
• Smooth Transitions: A broad platform and tuned heel/forefoot stabilize the foot and promote a stable heel-to-toe roll.
• Medical Acceptance: Certified PDAC A5500 diabetic shoe and granted the APMA Seal of Acceptance, indicating attention to foot health and design.

Who It's For

The Glycerin 22 is best for neutral runners and active women who prioritize cushioning and comfort over maximal speed or motion control. It works well for road running, gym sessions, cross training, and long days on your feet because of its plush midsole and roomy toe area.

Those who require strong stability features or corrective support should look at models with guidance systems, such as Brooks Glycerin GTS styles, rather than this neutral shoe. Also, competitive racers seeking minimal weight and maximal responsiveness may prefer a lighter, less cushioned trainer.

Pros & Cons

Pros

• Exceptional cushioning that provides comfortable, soft landings for longer runs and everyday wear.
• Accommodating knit upper with room in the toe box and a padded heel that customers report as comfortable.
• Broad platform and tuned geometry deliver stable, smooth transitions from heel to toe.
• Recognized by APMA and certified as a PDAC A5500 diabetic shoe, supporting foot health considerations.

Cons

• Some customers feel the price is high compared with expectations, even if they find the shoe worth it for comfort.
• Neutral design means it is not the best choice for runners who need strong arch or motion-control corrections.

Specifications

Our Verdict

The Brooks Womens Glycerin 22 is a top choice for neutral runners and active women who want maximum cushioning and comfortable transitions without sacrificing a stable platform. It represents good value when plush comfort, a roomy fit, and foot-health certifications matter more than ultralight race performance.

Frequently Asked Questions

Are these shoes suitable for long runs?
Yes. The plush DNA Tuned midsole and broad platform make them comfortable for longer road runs and extended wear.

Do they provide arch support?
They offer neutral support and cushioning but are not designed as a motion-control or high-arch corrective shoe; choose a GTS or stability model if you need extra support.

Are they good for people with foot health concerns?
The Glycerin 22 is PDAC A5500 certified and carries the APMA Seal of Acceptance, indicating attention to foot-friendly design and accommodations.