Brooks Womens Glycerin 22 Neutral Running Shoe - Plush Cushioning APMA

In this review of the Brooks Womens Glycerin 22 Neutral Running Shoe the bottom line is simple: it is best for runners and walkers who prioritize maximum cushioning and smooth transitions. The Glycerin 22 stands out because of its DNA Tuned midsole that blends larger heel cells and smaller forefoot cells, delivering soft landings and responsive toe-offs; combined with an accommodating double jacquard knit upper, it feels plush yet supportive for long miles or all-day wear.

Key Features

• DNA Tuned Cushion: Larger cells in the heel provide soft, plush landings while smaller forefoot cells encourage a responsive toe-off for a balanced ride.
• Neutral Support: Designed as a neutral shoe, it offers the maximum amount of cushioning without added corrective structure, suitable for road running and gym use.
• Accommodating Fit: The double jacquard knit upper flexes with the foot to provide breathability and a roomy toe box that many wearers find comfortable for long distances.
• Smooth Transitions: A broad platform and tuned heel-to-forefoot geometry help stabilize the foot and smooth heel-to-toe transitions during runs or walks.
• Medical Acceptance: Certified as a PDAC A5500 diabetic shoe and awarded the APMA Seal of Acceptance, which indicates a design mindful of foot health and comfort.

Who It's For

The Glycerin 22 is aimed at neutral runners, daily walkers, and anyone seeking plush cushioning for long training runs or extended periods on their feet. It is especially useful for people who need a soft, protective sole and appreciate a roomy toe box for comfort.

Runners who require strong stability or motion control should consider a support model instead, such as Brooks Glycerin GTS 22, while those wanting a very lightweight racing shoe may find the Glycerin 22 heavier and plusher than needed.

Pros & Cons

Pros

• Exceptional cushioning and soft ride from the DNA Tuned midsole.
• Comfortable, breathable upper with an accommodating fit and roomy toe box.
• Certified PDAC A5500 and APMA accepted, supporting foot health concerns.
• Stable broad platform that smooths transitions and supports longer movement.

Cons

• Some customers report inconsistent sizing, with a few finding them smaller than expected.
• Not the best choice for runners who need built-in corrective support or a minimalist feel.

Specifications

Our Verdict

The Brooks Womens Glycerin 22 is a strong pick for runners and walkers who want maximum cushioning, a plush ride, and an accommodating fit that performs well on roads and in the gym. While sizing opinions vary, its supportive platform and validated foot-health credentials make it a worthwhile choice for those prioritizing comfort and smooth transitions.

Frequently Asked Questions

Are these shoes good for long runs?
Yes, the DNA Tuned midsole and broad platform provide cushioning and stability suited to long road runs.

Do they provide corrective support?
No, the Glycerin 22 is a neutral shoe; choose the Glycerin GTS 22 for added support.

Are they suitable for people with foot health concerns?
They are PDAC A5500 certified and have the APMA Seal of Acceptance, which indicates the design meets certain foot health standards.