Brooks Womens Glycerin 22 Neutral Running Shoe - Plush Cushioning PDAC

In this review of the Brooks Womens Glycerin 22 Neutral Running Shoe the bottom line is simple: this is a plush, highly cushioned neutral trainer designed for runners and walkers who prioritize comfort and smooth transitions. The shoe stands out for its DNA Tuned midsole that blends larger heel cells with smaller forefoot cells for soft landings and responsive toe-offs, and it carries both APMA acceptance and PDAC A5500 diabetic shoe certification, which reinforces its focus on comfort and foot health.

Key Features

• Neutral support: Delivers the maximum level of cushioning without added pronation control, making it suitable for neutral runners and general gym use.
• DNA Tuned cushion: Larger cells in the heel and smaller cells in the forefoot create soft landings and lively toe-offs for smoother transitions.
• Accommodating fit: The double jacquard knit upper stretches to fit various foot shapes while keeping breathability and durability in key areas.
• Smooth, stable transitions: A broad platform and tuned heel and forefoot help stabilize the foot and encourage even heel-to-toe movement.
• Medical certifications: PDAC A5500 diabetic shoe certification and the APMA Seal of Acceptance indicate attention to foot health and supportive design.

Who It's For

The Glycerin 22 is best for women who want maximum cushioning for road running, long walks, or cross training and who value a soft, plush sole and roomy toe box. Runners with neutral gaits and people seeking a shoe cleared for diabetic foot care will appreciate the comfort and certifications.

Those who need significant stability or corrective support should look at a stability cousin rather than this model, and people who prefer a very snug, performance race fit may find the Glycerin 22 too cushioned and cushy for fast tempo runs.

Pros & Cons

Pros

• Exceptional cushioning that helps reduce fatigue on long road runs and extended walks.
• Accommodating knit upper provides a comfortable, breathable fit for wider toes and varied foot shapes.
• Certified PDAC A5500 and APMA acceptance, useful for customers prioritizing foot health.
• Stable platform and tuned transitions make gait feel smooth underfoot.

Cons

• Some customers report inconsistent sizing, with a few noting the fit runs small, so trying on before buying is advised.
• Its maximal cushioning can feel bulky for runners who want a very responsive, lightweight race shoe.

Specifications

Our Verdict

The Brooks Womens Glycerin 22 is a strong choice for runners and walkers who want plush cushioning, a breathable accommodating fit, and smooth heel-to-toe transitions. Its medical certifications add credibility for customers focused on foot health, though buyers should verify sizing because fits can vary; overall it offers reliable comfort and good long-run value.

Frequently Asked Questions

Are these shoes good for long distance road running?
Yes. The high level of cushioning and stable platform make the Glycerin 22 comfortable for long road miles and extended walking.

Do they offer support for overpronation?
No. This is a neutral shoe; those needing added stability should consider a stability model instead.

How does the sizing run?
Customer reports vary; some find them true to size while others say they run small, so trying on or checking return options is recommended.