Brooks Womens Glycerin 22 Neutral Running Shoe - Plush Cushioning Road

In this review the Brooks Womens Glycerin 22 Neutral Running Shoe stands out as a top choice for women seeking maximum cushioning and smooth transitions on roads or at the gym. The single biggest reason to buy is the updated DNA Tuned midsole, which blends dual-size cells for a soft landing in the heel and a responsive toe-off. Reviewers consistently praise comfort and support, and the shoe's certifications give extra confidence for people needing a considerate fit for foot health.

Key Features

• DNA Tuned Cushion: Larger cells in the heel deliver plush landings while smaller forefoot cells promote energetic toe-offs for a balanced ride.
• Neutral Support: Provides a neutral platform with the maximum available cushioning, suitable for road running and cross training.
• Accommodating Fit: The double jacquard knit upper stretches where needed for a roomy toe box and reliable breathability.
• Smooth Transitions: A broad platform plus a tuned heel and forefoot stabilize the foot and smooth heel-to-toe motion.
• Health Certifications: Certified PDAC A5500 for diabetic use and carries the APMA Seal of Acceptance, offering assurance for foot health needs.

Who It's For

The Glycerin 22 is best for runners and walkers who prioritize maximum cushioning and a smooth, stable ride. It suits road runners, people who cross train, and anyone who spends long hours on their feet and wants a soft, protective sole with a roomy forefoot.

Those who need strong motion control or heavy pronation support should look at stability models such as the Glycerin GTS series instead. Also, shoppers who rely on a precise, consistent fit should note some customers found sizing runs small and may want to try a size up.

Pros & Cons

Pros

• Exceptional cushioning that lets users walk long distances without pain and helps protect knees and hips.
• Comfortable, roomy toe box from the engineered double jacquard knit upper that enhances breathability.
• Stable, smooth heel-to-toe transitions thanks to the broad platform and tuned midsole geometry.
• Health-minded certifications with PDAC A5500 and APMA Seal support use for sensitive feet.

Cons

• Sizing can be inconsistent for some shoppers, with multiple reports that the shoe runs small.
• As a neutral shoe, it lacks the built-in corrective support some overpronators require.

Specifications

Model	Glycerin 22
Support	Neutral
Midsole Technology	DNA Tuned dual-size cell cushioning
Upper	Double jacquard knit, breathable and flexible
Certifications	PDAC A5500 Diabetic shoe; APMA Seal of Acceptance
Predecessor	Glycerin 21

Our Verdict

The Glycerin 22 is a strong pick for women who want plush cushioning and smooth, stable transitions on daily runs or long walks. It represents good value for anyone prioritizing comfort and foot-health assurances, though shoppers should verify fit since sizing has varied among customers.

Frequently Asked Questions

Are these shoes good for long walks?
Yes. Customers report excellent cushioning and support that make long distances comfortable for knees and hips.

Do these shoes offer stability for overpronation?
No. The Glycerin 22 is a neutral shoe; those needing added support should consider stability variants like the Glycerin GTS.

How do these fit?
The upper is accommodating and roomy in the toe box, but some buyers say sizing runs small, so consider trying a half size up if between sizes.