Brooks Womens Glycerin 22 Neutral Running Shoe - Plush Cushioning same
Brooks Womens Glycerin 22 Neutral Running Shoe - Plush Cushioning same
Price subject to change. Tap below for current.
Couldn't load pickup availability
In this review the Brooks Womens Glycerin 22 stands out as a neutral running shoe built for runners and walkers who prioritize premium cushioning and smooth transitions. The single biggest reason to buy is the updated DNA Tuned cushion, which blends larger heel cells and smaller forefoot cells to deliver plush landings and responsive toe-offs. The shoe also brings an accommodating knit upper and a broad platform for stability, making it a comfortable daily trainer for road miles, gym sessions, or long walks.
Key Features
- DNA Tuned Cushion: Larger midsole cells in the heel create soft, forgiving landings while smaller forefoot cells enable a springy, energetic toe-off for smoother gait transitions.
- Neutral Support: Designed as a neutral shoe that offers maximum cushioning without added motion control, suitable for runners who do not need corrective support.
- Accommodating Fit: The double jacquard knit upper stretches and breathes to reduce pressure points and provides extra room in the toe box for comfort during long wear.
- Stable Platform: A broad sole base and tuned heel/forefoot geometry stabilize the foot and promote consistent heel-to-toe movement.
- Medical and Podiatric Approval: Certified as a PDAC A5500 Diabetic shoe and granted the APMA Seal of Acceptance, indicating attention to fit and foot health.
Who It's For
The Glycerin 22 is best for neutral runners and active walkers who want maximum cushioning on road runs, treadmill sessions, or everyday wear. Its plush midsole and roomy toe box suit those who often cover long distances on hard surfaces and need a comfortable, forgiving ride.
Runners who require strong stability or corrective support should look at stability-specific models such as the Brooks Glycerin GTS 22. Minimalist runners who prefer a firmer, low-profile feel will also find the thick cushioning of the Glycerin 22 too soft for their tastes.
Pros & Cons
Pros
- Excellent cushioning through DNA Tuned technology for soft landings and responsive toe-offs.
- Accommodating, breathable knit upper gives a comfortable fit with extra room in the toe box.
- Stable, broad platform helps create smooth heel-to-toe transitions and a confident ride.
- Backed by PDAC and APMA acceptance for foot health and diabetic-friendly fit.
Cons
- May feel bulky or overly soft for runners who prefer a firm, minimal ride.
- Opinions vary on sizing and value for money, so trying on for fit is recommended.
Specifications
| Model | Glycerin 22 |
| Support type | Neutral |
| Midsole tech | DNA Tuned with varied cell sizes |
| Upper | Double jacquard knit, breathable |
| Platform | Broad platform for stable transitions |
| Certifications | PDAC A5500 Diabetic shoe; APMA Seal of Acceptance |
Our Verdict
The Brooks Womens Glycerin 22 is an excellent choice for runners and walkers seeking plush cushioning, a roomy fit, and smooth transitions. Its DNA Tuned midsole and stable platform offer comfort and responsiveness for road running and everyday training, making it a good value for those prioritizing long-run comfort and foot health.
Frequently Asked Questions
Are these shoes good for long-distance road running?
Yes, the maximum cushioning and stable platform make them well suited to long road runs and extended walking sessions.
Do they provide support for overpronation?
No, the Glycerin 22 is a neutral shoe; choose the GTS/stability model if you need corrective support.
Is the fit narrow or roomy?
The double jacquard knit upper offers an accommodating fit with extra toe-box room, though some shoppers report mixed sizing impressions so try before committing.
Editor's Take
The Brooks Womens Glycerin 22 delivers plush, DNA Tuned cushioning, a roomy knit fit, and stable transitions, making it a strong choice for neutral runners and walkers who prioritize comfort and foot health.

Recently viewed
Recently viewed products will appear here as customers browse the store.