Brooks Womens Glycerin 22 Neutral Running Shoe - Plush (Style 232S)

Our review of the Brooks Womens Glycerin 22 finds it best suited to runners and walkers who want maximum, soft cushioning without corrective support. The single biggest reason to consider these shoes is the updated DNA Tuned midsole that marries plush landings with responsive toe-offs, delivering very comfortable long walks and runs while also meeting the needs of people requiring a certified diabetic shoe. Overall the Glycerin 22 focuses on a luxurious, stable ride rather than corrective motion control.

Key Features

• Neutral Support: Provides neutral support with the maximum amount of cushioning, making it ideal for road running, cross training, or gym use where comfort is the priority.
• DNA Tuned Cushion: Larger midsole cells in the heel give soft landings while smaller forefoot cells encourage an energetic toe-off for smooth strides.
• Accommodating Fit: The double jacquard knit upper stretches to fit a range of foot shapes while remaining breathable and durable during long wear.
• Smooth Transitions: A broad platform combined with a tuned heel and forefoot stabilizes the foot and smooths heel-to-toe motion for steadier runs.
• Medical Certifications: Certified as a PDAC A5500 Diabetic shoe and granted the APMA Seal of Acceptance, indicating it meets standards for accommodating foot health.

Who It's For

The Glycerin 22 is aimed at women who prioritize cushioning and a soft ride: long-distance walkers, road runners who prefer plush soles, and anyone needing an accommodating shoe for sensitive feet or diabetic footcare. Its neutral platform fits runners who do not require extra stability or corrective guidance.

Runners who need strong medial support or motion control should look at support-specific models instead. If very precise sizing is critical, note that customer reports vary on fit so trying a pair on or ordering with return options in mind is advisable.

Pros & Cons

Pros

• Exceptional cushioning and a soft, squishy sole that users say allows long walks without pain.
• Supportive platform that helps knees and hips feel more comfortable during activity.
• Roomy toe box and breathable knit upper provide comfort and reduce hotspot issues.
• Certified PDAC A5500 and APMA accepted, making it a solid choice for foot health concerns.

Cons

• Sizing reports are mixed, with some customers finding the shoe runs smaller than expected.
• As a maximal cushioning neutral shoe, it may not suit runners seeking firm responsiveness or strong corrective support.

Specifications

Brand	Brooks
Model	Glycerin 22
Support Type	Neutral
Midsole Technology	DNA Tuned with dual-size cells
Upper	Double jacquard knit, breathable and flexible
Certifications	PDAC A5500 Diabetic shoe, APMA Seal of Acceptance

Our Verdict

The Brooks Womens Glycerin 22 is a strong pick for anyone who values plush cushioning and a stable, comfortable ride, including those with sensitive or diabetic feet. Its DNA Tuned midsole and roomy knit upper deliver long-wear comfort and smooth transitions, offering good value for buyers prioritizing cushioning over corrective support.

Frequently Asked Questions

Do these shoes provide stability for overpronation?
They are a neutral shoe focused on cushioning; runners needing extra stability should choose a support-specific model.

Are they good for long-distance walking?
Yes - customers report the soft cushioning and roomy toe box make them comfortable for long walks and extended wear.

Do they fit true to size?
Sizing feedback is mixed; some find them smaller than expected, so trying them on or checking return options is recommended.