Brooks Womens Glycerin 22 Neutral Running Shoe - Plush (Style 3Y3B)

Our review of the Brooks Womens Glycerin 22 finds it best for women seeking a plush, neutral road running shoe that prioritizes cushioning and smooth transitions. The single biggest reason to buy is its updated DNA Tuned cushion, which blends larger heel cells and smaller forefoot cells to deliver soft landings and energised toe-offs without sacrificing a stable platform. It is also certified as a PDAC A5500 diabetic shoe and carries the APMA Seal of Acceptance, making it appealing to buyers who need validated comfort and foot health considerations.

Key Features

• Neutral support: Provides the maximum level of cushioning in a neutral setup, ideal for runners who want comfort without added motion control.
• DNA Tuned cushion: Larger cells in the heel create plush landings while smaller forefoot cells promote responsive toe-offs for smoother effort across each stride.
• Accommodating fit: A double jacquard knit upper offers flexibility and breathability while allowing extra room in the toe box for comfort.
• Smooth transitions: A broad platform with tuned heel and forefoot geometry stabilizes the foot and helps heel-to-toe roll feel seamless.
• Foot health certifications: Certified PDAC A5500 for diabetic use and awarded the APMA Seal of Acceptance, supporting foot care concerns.

Who It's For

The Glycerin 22 suits recreational and road runners who value maximum cushioning and a soft ride, as well as walkers, gym users, and cross trainers who prefer plush support for longer periods on their feet. It is a strong choice for those with wider toe demands thanks to the accommodating knit upper and the roomy forefoot feel many customers mention.

Runners who need corrective stability or strong pronation control should consider a support version such as the Glycerin GTS 22 instead, since this model is explicitly a neutral shoe. Also, budget buyers who prioritize low cost above cushioning may find the price a drawback despite the shoe's quality construction.

Pros & Cons

Pros

• Exceptional cushioning that absorbs impact well for road running and daily wear.
• Comfortable, breathable knit upper with a roomy toe area for foot comfort.
• Stable, broad platform that smooths transitions from heel to toe.
• Certified PDAC A5500 and APMA Seal, supporting foot health credentials.

Cons

• Higher price point noted by some customers compared with rivals offering similar features.

Specifications

Brand	Brooks
Model	Glycerin 22
Support Type	Neutral
Cushion Technology	DNA Tuned midsole with dual-size cells
Upper	Double jacquard knit, breathable and flexible
Certifications	PDAC A5500 diabetic shoe; APMA Seal of Acceptance

Our Verdict

The Brooks Womens Glycerin 22 is a top choice for runners and active women who want the plushest neutral cushioning Brooks offers, paired with a stable platform and an accommodating fit. It is good value for those prioritising comfort and foot health certifications, though shoppers focused only on price may prefer less expensive alternatives.

Frequently Asked Questions

Are these shoes good for wide feet?
Yes, the double jacquard knit upper and roomy toe box provide an accommodating fit that many customers report as comfortable for wider feet.

Is this shoe suitable for diabetics?
Yes, the Glycerin 22 is certified PDAC A5500 and carries the APMA Seal of Acceptance, indicating suitability for diabetic foot health needs.

Does this model offer stability for pronation?
No, the Glycerin 22 is a neutral shoe; those needing added support should look at the Glycerin GTS 22 or other support models.