Brooks Womens Glycerin 22 Neutral Running Shoe - Plush (Style 8LYV)

Our review of the Brooks Womens Glycerin 22 finds it best suited to runners and walkers who prioritize a plush, protected ride over minimal weight or aggressive responsiveness. The single biggest reason to consider these shoes is the DNA Tuned midsole, which blends larger heel cells and smaller forefoot cells to deliver soft landings and energetic toe-offs while preserving a smooth heel-to-toe transition. As a certified PDAC A5500 diabetic shoe with the APMA Seal of Acceptance, it also provides reassuring comfort and support for long distances and everyday wear.

Key Features

• DNA Tuned Cushion: Larger cells in the heel create soft, plush landings while smaller forefoot cells encourage a responsive toe-off for smoother stride energy transfer.
• Neutral Support: The shoe offers neutral biomechanics with maximum cushioning, making it appropriate for road running, gym sessions, and general cross training.
• Accommodating Fit: The double jacquard knit upper stretches for a comfortable, breathable fit that adapts to the foot without feeling constrictive.
• Smooth Transitions: A broad platform combined with a tuned heel and forefoot helps stabilize the foot and smooth heel-to-toe movements during longer walks and runs.
• Medical Certification: Certified PDAC A5500 and awarded the APMA Seal of Acceptance, signaling it meets design standards for foot health and diabetic needs.

Who It's For

The Glycerin 22 is ideal for neutral runners who want maximum cushioning and a plush ride for road miles, recovery runs, or long walks; it also suits anyone who needs a roomy toe box and supportive cushioning for daily wear. Runners with knee or hip comfort concerns may appreciate the soft sole and stabilizing platform that reduce impact and support natural transitions.

These are less appropriate for runners seeking a lightweight racing shoe, maximal responsiveness for speed workouts, or an aggressive stability platform; those needs are better met by performance-focused or support-specific models rather than this highly cushioned neutral trainer.

Pros & Cons

Pros

• Exceptional cushioning and comfort for long distance walking and easy runs.
• Accommodating knit upper provides a breathable, flexible fit with a roomy toe box.
• Certified PDAC A5500 and APMA accepted, suitable for diabetic foot concerns and supportive daily wear.
• Stable, broad platform that aids smooth heel-to-toe transitions without feeling wobbly.

Cons

• Sizing reports vary and some users find the fit smaller than expected, so trying on or checking fit guidance is advised.
• The plush cushioning adds weight compared with lightweight trainers, making it less ideal for fast tempo runs or racing.

Specifications

Brand	Brooks
Model	Glycerin 22
Support Type	Neutral
Midsole Technology	DNA Tuned with dual-size cells
Upper	Double jacquard knit upper
Certifications	PDAC A5500 certified; APMA Seal of Acceptance

Our Verdict

The Brooks Womens Glycerin 22 is a strong choice for runners and walkers seeking a plush, supportive neutral trainer with medical-minded certifications and a forgiving ride. It represents good value for those prioritizing comfort, cushioning, and smooth transitions, though buyers should confirm fit before committing if they typically need a precise size.

Frequently Asked Questions

Do these shoes offer stability for overpronation?
The Glycerin 22 is a neutral shoe designed for maximum cushioning rather than firm stability; those needing extra support should consider support-specific models.

Are these suitable for diabetic feet?
Yes, the shoe is PDAC A5500 certified and has the APMA Seal of Acceptance, indicating suitability for diabetic foot care and therapeutic needs.

Do they run true to size?
Customer feedback is mixed on sizing, with some reporting a smaller fit; trying them on or following a sizing guide is recommended.