Brooks Womens Glycerin 22 Neutral Running Shoe - Plush (Style 9DPP)

Our review of the Brooks Womens Glycerin 22 finds it is a go-to choice for runners and walkers who prioritize maximum cushioning and smooth transitions. The shoe's standout feature is its DNA Tuned cushion, which blends larger heel cells for soft landings with smaller forefoot cells for responsive toe-offs, creating a balanced ride that feels both plush and energetic. Certified as a PDAC A5500 Diabetic shoe and bearing the APMA Seal of Acceptance, the Glycerin 22 also appeals to those needing an accommodating, foot-friendly fit.

Key Features

• Neutral support: Provides neutral support while delivering the most cushioning in the Glycerin line for comfortable road runs and cross training.
• DNA Tuned cushion: Larger heel cells create soft, plush landings and smaller forefoot cells offer springy toe-offs for smoother stride transitions.
• Accommodating fit: The new double jacquard knit upper stretches to fit a range of foot shapes while remaining breathable and durable.
• Stability through platform: A broad midsole platform helps stabilize the foot and smooth heel-to-toe motion without adding rigid support features.
• Medical endorsements: Certified PDAC A5500 and APMA accepted, making it suitable for those seeking medically recognized footwear benefits.
• Versatile use: Suited for road running, gym sessions, and long walks where plush cushioning and comfort are priorities.

Who It's For

The Glycerin 22 is best for women who want maximum cushioning in a neutral shoe: long-distance road runners, walkers who cover lots of pavement, and gym-goers who prefer a soft underfoot feel. Its roomy toe box and soft sole are frequently praised by customers who need extra comfort for long days on their feet.

Runners who require strong medial guidance or corrective stability should look at the Glycerin GTS version for added support, and those who prefer a firmer, race-oriented ride may find the plush cushioning too soft for tempo work or racing.

Pros & Cons

Pros

• Excellent cushioning with a soft, plush feel that reduces impact on knees and hips.
• Accommodating, breathable upper that fits a variety of foot shapes comfortably.
• Stable broad platform and tuned transitions that make heel-to-toe motion feel smooth.
• Medically certified PDAC A5500 and APMA acceptance for added confidence in foot health benefits.

Cons

• Sizing has mixed feedback; some customers report the shoe runs smaller than expected, so trying on before committing is advised.
• The very plush sole may feel too soft for runners seeking a firm, performance-oriented ride.

Specifications

Brand	Brooks
Model	Womens Glycerin 22
Support	Neutral
Cushioning Technology	DNA Tuned
Upper	Double jacquard knit
Medical Certification	PDAC A5500 certified; APMA Seal of Acceptance
Best Use	Road running, cross training, walking

Our Verdict

The Brooks Womens Glycerin 22 is a strong choice for anyone who wants maximal cushioning and smooth transitions in a neutral running shoe. It delivers a comfortable, roomy fit and medically recognized benefits that make it good value for walkers, long-distance runners, and those needing extra underfoot comfort; buyers seeking firmer performance or added stability should consider alternatives.

Frequently Asked Questions

Are these shoes good for long walks?
Yes. Customers report the plush sole and roomy toe box make the Glycerin 22 comfortable for long distances on pavement.

Do they provide stability for overpronation?
No. The Glycerin 22 is a neutral shoe; those who need extra medial support should try the Glycerin GTS version.

How does sizing run?
Opinions vary; some find them true to size while others say they run small, so try before you buy or order with flexible return options.