Brooks Womens Glycerin 22 Neutral Running Shoe - Plush (Style BQ2N)

In this review of the Brooks Womens Glycerin 22 Neutral Running Shoe the bottom line is simple: this is a cushioned, neutral trainer for runners and gym users who prioritize comfort and smooth transitions. The most compelling reason to buy is the updated DNA Tuned cushion, which blends larger heel cells for soft landings with smaller forefoot cells for responsive toe-offs, delivering a plush but energetic feel on road runs and everyday workouts.

Key Features

• Neutral Support: Provides neutral support while maximizing cushioning, making it versatile for road running, cross training, and gym sessions.
• DNA Tuned Cushion: Larger midsole cells in the heel and smaller forefoot cells work together to absorb impact and return energy for smoother stride transitions.
• Accommodating Fit: The double jacquard knit upper offers a flexible fit that adapts to the foot while remaining breathable and durable for longer wear.
• Smooth, Stable Transitions: A broad platform and tuned heel/forefoot geometry stabilize the foot and encourage balanced heel-to-toe movement.
• Medical-Seal Acceptance: Certified as a PDAC A5500 diabetic shoe and awarded the APMA Seal of Acceptance for foot health and safety.

Who It's For

The Glycerin 22 is best for recreational and committed runners who want maximum cushioning without added guidance or strong corrective elements; it fits well for road runners, treadmill users, and anyone who spends time on their feet at the gym. The plush feel and roomy toe box suit people who prioritize comfort, toe splay, and a padded heel for longer wear.

Runners who need strong stability or motion control should look at supportive alternatives like the Glycerin GTS version with added guidance. Also, if you want a minimalist, low-cushion shoe for speedwork, this model's emphasis on plush cushioning may feel too soft.

Pros & Cons

Pros

• Excellent cushioning that many customers describe as very comfortable for long runs and daily wear.
• Accommodating upper provides a roomy, breathable fit and reduces pressure points in the toe box.
• Reliable stability from the broad platform and tuned transitions without adding rigid support elements.
• Recognized for foot health with PDAC A5500 diabetic shoe certification and the APMA Seal of Acceptance.

Cons

• The plush construction can feel heavy or less responsive for runners seeking a fast, lightweight shoe for tempo work.
• Some buyers note that the price feels high, even though many still call it good value for comfort and build quality.

Specifications

Our Verdict

The Brooks Womens Glycerin 22 is a top choice for runners and gym users who want maximum cushioning, a roomy fit, and smooth heel-to-toe transitions. Its DNA Tuned midsole and stable platform make it good value for those who prioritize comfort and foot health, though runners after a very lightweight, race-ready ride should consider other options.

Frequently Asked Questions

Are these shoes good for everyday walking?
Yes, the plush cushioning and broad platform make them comfortable for daily walking and standing.

Do they provide arch support for overpronation?
They are a neutral shoe, so they do not add strong corrective support; choose the Glycerin GTS or a stability model for overpronation.

Are they suitable for diabetic feet?
Yes, the Glycerin 22 is certified as a PDAC A5500 diabetic shoe and carries the APMA Seal of Acceptance.