Brooks Womens Glycerin 22 Neutral Running Shoe - Plush (Style FCD1)

Our review of the Brooks Womens Glycerin 22 finds it is a cushioning-first neutral road shoe best suited to runners and walkers who prioritize comfort and smooth transitions. The single biggest reason to consider the Glycerin 22 is its updated DNA Tuned midsole, which blends larger heel cells and smaller forefoot cells to deliver soft landings without losing a responsive toe-off. It also carries trusted certifications for diabetic-friendly wear and has the APMA Seal of Acceptance, making it a compelling option for anyone needing dependable cushioning and supportive stability for daily miles.

Key Features

• DNA Tuned Cushion: Larger cells in the heel and smaller cells in the forefoot combine for plush landings and energetic toe-offs that preserve a smooth stride.
• Neutral Support: The shoe provides neutral support with the maximum amount of cushioning, ideal for road running, cross training, or long walks.
• Accommodating Fit: A new double jacquard knit upper offers flexibility and breathability while accommodating a range of foot shapes.
• Smooth, Stable Transitions: A broad platform with a tuned heel and forefoot helps stabilize the foot and smooth the heel-to-toe roll.
• Certified Comfort: Certified as a PDAC A5500 diabetic shoe and awarded the APMA Seal of Acceptance for foot health and comfort.

Who It's For

The Glycerin 22 is best for neutral runners, walkers, and gym-goers who want maximum cushioning without added support structures. It works well for road miles, recovery runs, and anyone who spends long periods on their feet and values a soft, protected ride.

Runners who need pronounced stability or corrective support should look at the Glycerin GTS 22 or other support models instead, while those seeking a very lightweight race-day shoe will likely find this model too cushioned and plush for high-speed performance.

Pros & Cons

Pros

• Exceptional cushioning that reduces impact on knees and hips for long walks or runs.
• Accommodating knit upper provides a comfortable, breathable fit for varied foot shapes.
• Certified PDAC A5500 and APMA Seal of Acceptance, indicating attention to foot health.

Cons

• Sizing opinions vary among customers, with some reporting runs small, so trying before buying or checking fit guidance is advised.

Specifications

Model	Glycerin 22
Support type	Neutral
Midsole technology	DNA Tuned with dual-size cells
Upper	Double jacquard knit
Certifications	PDAC A5500 diabetic shoe, APMA Seal of Acceptance
Predecessor	Glycerin 21

Our Verdict

The Brooks Womens Glycerin 22 is an excellent choice for anyone who prioritizes plush cushioning and a smooth ride for everyday running and walking. Its DNA Tuned midsole and broad platform deliver reliable comfort and stable transitions, and the diabetic and APMA certifications add real value for foot health-conscious buyers. Consider sizing carefully, but for comfort-first runners this shoe is worth the investment.

Frequently Asked Questions

Are these shoes good for long walks?
Yes. Customers report comfortable long-distance walking with excellent cushioning and support for knees and hips.

Do these provide motion control for overpronation?
No. The Glycerin 22 is a neutral shoe; those needing added support should consider the Glycerin GTS 22 or a stability model.

How does sizing run?
Customers disagree on sizing and some say they run small, so checking fit guides or trying them on is recommended before purchase.