Brooks Womens Glycerin 22 Neutral Running Shoe - Plush (Style FTFT)

Our review of the Brooks Womens Glycerin 22 finds it best suited to runners and walkers who prioritize maximum cushioning and smooth transitions. The standout reason to buy is the new DNA Tuned midsole that balances soft landings with responsive toe-offs, delivering a plush yet energetic ride that works well for road running, gym sessions, and long walks. The shoe's APMA Seal and PDAC A5500 diabetic certification also make it a thoughtful option for those needing proven comfort and foot-health credentials.

Key Features

• Neutral Support: Provides a neutral platform that maximizes cushioning for road runs and cross training without imposing corrective support.
• DNA Tuned Cushion: Larger midsole cells in the heel create soft landings while smaller forefoot cells encourage responsive toe-offs.
• Accommodating Fit: The double jacquard knit upper stretches where needed and maintains breathability for long wear.
• Smooth Transitions: A broad platform plus tuned heel and forefoot deliver stable, heel-to-toe motion during varied paces.
• Foot-Health Certifications: Certified PDAC A5500 and awarded the APMA Seal of Acceptance, indicating attention to diabetic and podiatric comfort.

Who It's For

The Glycerin 22 is ideal for neutral runners who want the maximum cushioning available in a daily trainer and for walkers who need long-distance comfort with good knee and hip support. Its roomy toe box and plush sole make it a comfortable choice for people who spend extended time on hard surfaces.

Runners who require strong stability or motion control should consider a support-focused model instead, such as the Glycerin GTS variant, while racers seeking a lightweight, fast shoe will likely find this model heavier and more cushioned than necessary.

Pros & Cons

Pros

• Exceptional cushioning that soaks up impact and reduces discomfort on long walks or runs.
• Supportive, smooth heel-to-toe transitions owing to the broad platform and tuned midsole.
• Comfortable, breathable knit upper with an accommodating fit and a roomy toe box.

Cons

• Sizing feedback varies; some customers report the shoe runs smaller than expected, so trying on or sizing up may be necessary.

Specifications

Brand	Brooks
Model	Glycerin 22 (women)
Support	Neutral
Midsole Technology	DNA Tuned with dual-size cells
Upper	Double jacquard knit, breathable and accommodating
Certifications	PDAC A5500 diabetic certified; APMA Seal of Acceptance

Our Verdict

The Brooks Womens Glycerin 22 is a strong choice for runners and walkers who want top-tier cushioning and a smooth, stable ride. With thoughtful foot-health certifications and an accommodating knit upper, it delivers noticeable comfort and good value for daily training and long-distance walking, though buyers should verify sizing before purchasing.

Frequently Asked Questions

Are these shoes suitable for long walks?
The generous cushioning and broad platform make them well suited to long walks and extended time on hard surfaces.

Do they provide stability for overpronation?
This is a neutral shoe; runners needing motion control should choose a stability variant like the Glycerin GTS.

How do they fit compared with previous models?
Customers report mixed sizing compared with the predecessor Glycerin 21, so trying on or considering a half size up can help ensure a comfortable fit.