Brooks Womens Glycerin 22 Neutral Running Shoe - Plush (Style GMG2)

In this review of the Brooks Womens Glycerin 22 Neutral Running Shoe the bottom line is simple: this is a plush, neutral running shoe built for runners and walkers who prioritize maximum cushioning and smooth transitions. The Glycerin 22 stands out for its DNA Tuned midsole that blends larger heel cells with smaller forefoot cells to deliver soft landings and responsive toe-offs, plus an accommodating knit upper that eases fit-related pressure points. It is a serious option for road running, cross training, or long days on your feet when comfort and stability matter most.

Key Features

• DNA Tuned Cushion: The midsole combines larger cells in the heel and smaller cells in the forefoot to create soft landings and responsive toe-offs for smoother stride transitions.
• Neutral Support: Designed as a neutral shoe, it offers the maximum amount of cushioning without added corrective support, suitable for runners who do not overpronate.
• Accommodating Fit: The double jacquard knit upper provides flexibility and breathability while accommodating wider or swollen feet comfortably.
• Smooth Stable Transitions: A broad platform and tuned heel and forefoot stabilize the foot and promote even heel-to-toe movement on roads and the gym floor.
• Medical Certifications: Certified as a PDAC A5500 diabetic shoe and bearing the APMA Seal of Acceptance, indicating attention to medical comfort and foot health.

Who It's For

The Glycerin 22 is aimed at neutral runners, walkers, and cross-training users who seek maximum cushioning and a soft, supportive ride for longer sessions or everyday wear. It suits people with knee or hip sensitivity who benefit from plush landing and stable transitions.

Runners who need strong corrective support should consider a stability model instead, such as the Glycerin GTS line. Also, those who require a very narrow fit may find the accommodating knit upper roomier than desired.

Pros & Cons

Pros

• Exceptional cushioning that reduces impact on long runs and long days of walking.
• Comfortable, roomy toe box and breathable knit upper that accommodates a range of foot shapes.
• Stable, broad platform with tuned transitions for smoother heel-to-toe movement.
• Recognized medical certifications that support foot health considerations.

Cons

• Sizing opinions vary; some customers find them smaller than expected, so careful fitting is recommended.
• As a neutral shoe, it lacks the added support some overpronators need.

Specifications

Brand	Brooks
Model	Glycerin 22
Support	Neutral
Midsole Technology	DNA Tuned with varied cell sizes
Upper	Double jacquard knit
Certifications	PDAC A5500 diabetic shoe, APMA Seal of Acceptance

Our Verdict

The Brooks Womens Glycerin 22 is an excellent choice for runners and active walkers who want maximum cushioning, smooth transitions, and an accommodating fit; its medical certifications add confidence for foot health. Those needing extra corrective support or a very narrow fit should look to stability or narrower models, but for neutral cushioning and comfort this shoe represents good value.

Frequently Asked Questions

Are these shoes good for long-distance road running?
The Glycerin 22's plush cushioning and stable platform make it well suited to long road miles and extended walking sessions.

Do they run true to size?
Customer reports vary; some find sizing smaller than expected, so try on or consult size guidance before purchasing.

Are they suitable for diabetic feet?
Yes, the model is PDAC A5500 certified and carries the APMA Seal, indicating it meets standards for diabetic and foot-health friendly design.