Brooks Womens Glycerin 22 Neutral Running Shoe - Plush (Style JWD1)

In this review of the Brooks Womens Glycerin 22 Neutral Running Shoe the bottom line is simple: this is a high-cushion, neutral trainer best suited to runners and active walkers who prioritize comfort and smooth transitions. The standout reason to buy is the updated DNA Tuned cushion, which balances a plush landing with an energetic toe-off so everyday runs and long miles feel less jarring. It is also notable as a certified PDAC A5500 diabetic shoe with the APMA Seal of Acceptance, which adds confidence for users who need an accommodating, foot-friendly fit.

Key Features

• Neutral support: Delivers maximum cushioning without added corrective structure, ideal for runners who do not need stability devices.
• DNA Tuned cushion: Larger heel cells create soft landings while smaller forefoot cells encourage a responsive toe-off for smoother gait transitions.
• Accommodating fit: The double jacquard knit upper stretches where needed to provide room in the toes and a secure, breathable wrap over the midfoot.
• Stable platform: A broad sole platform stabilizes the foot during heel-to-toe movement to reduce awkward shifts in stride.
• Medical-friendly design: Certified PDAC A5500 and APMA-accepted, making it a reliable option for people who need extra interior room and protective features.

Who It's For

The Glycerin 22 is aimed at women seeking a plush, neutral running shoe for road running, cross training, or general gym use where cushioning and comfort are priorities. Its cushioning and roomy toe box also make it appealing to walkers and anyone who wants a comfortable shoe for long periods on their feet.

Runners who need strong corrective support or severe pronation control should look at the Glycerin GTS 22 or dedicated stability models instead, since this is specifically built for neutral support and maximum cushioning rather than motion control.

Pros & Cons

Pros

• Excellent cushioning that many customers describe as plush and comfortable for long wear.
• Accommodating fit with a roomy toe area and padded heel that customers report fits well without pinching.
• Certified PDAC A5500 and APMA Seal of Acceptance provide assurance for diabetic or sensitive feet.

Cons

• Some buyers may find the price higher than expected despite the quality and features.

Specifications

Our Verdict

The Brooks Womens Glycerin 22 is an excellent choice for runners and active users who want maximum cushioning, an accommodating fit, and smooth heel-to-toe transitions. Its medical certifications and plush DNA Tuned midsole make it a worthwhile investment for those prioritizing comfort and foot health, while runners needing added stability should consider alternative models.

Frequently Asked Questions

Are these shoes good for long runs?
Yes, the Glycerin 22s offer plush cushioning and smooth transitions that suit longer road runs and extended time on your feet.

Do they provide arch support?
They are neutral shoes with cushioning; customers report adequate support but not added corrective arch control compared with stability models.

Are they suitable for people with diabetes?
Yes, the shoe is PDAC A5500 certified and carries the APMA Seal, indicating it meets standards for accommodating diabetic footwear needs.