Brooks Womens Glycerin 22 Neutral Running Shoe - Plush (Style K1QV)

Our review of the Brooks Womens Glycerin 22 finds it best suited for runners and gym-goers who prioritize maximum cushioning and a smooth ride. The single biggest reason to buy is the DNA Tuned midsole that blends larger heel cells and smaller forefoot cells for plush landings and responsive toe-offs, delivering a noticeably softer, more energized feel than its predecessor while maintaining a neutral platform. The shoe also brings an accommodating knit upper and a broad platform that help create stable, comfortable runs and everyday wear.

Key Features

• DNA Tuned Cushion: Larger midsole cells in the heel provide soft, plush landings while smaller cells in the forefoot create a more responsive toe-off for efficient transitions.
• Neutral Support: Designed as a neutral running shoe, it provides maximum cushioning without added motion control, suitable for road running and cross training.
• Accommodating Fit: The double jacquard knit upper offers stretch and breathability, giving room in the toe box and a secure, padded heel for longer comfort.
• Smooth, Stable Transitions: A broad platform combined with a tuned heel and forefoot smooths heel-to-toe movement for steady strides.
• Medical Approvals: Certified as a PDAC A5500 diabetic shoe and awarded the APMA Seal of Acceptance, supporting foot health for those who need it.

Who It's For

The Glycerin 22 is ideal for runners who want a highly cushioned, neutral shoe for road miles, recovery runs, or long gym sessions where comfort and soft landings are priorities. Its roomy toe box and padded heel also appeal to walkers and anyone who spends long periods on their feet.

Runners who need structured motion control or high stability should look at the Glycerin GTS 22 or a stability-specific model instead; likewise, those seeking an ultra-lightweight racing shoe will find the Glycerin 22 heavier and more focused on plush comfort than speed.

Pros & Cons

Pros

• Exceptional cushioning with a responsive feel at toe-off thanks to the DNA Tuned midsole.
• Comfortable, breathable fit from the double jacquard knit upper with noticeable room in the toe box.
• Broad platform and tuned geometry deliver smooth, stable heel-to-toe transitions.
• Certified PDAC A5500 diabetic shoe and APMA accepted, adding credibility for foot health.

Cons

• Higher level of cushioning makes it less suitable for runners seeking a minimal or very lightweight race shoe.
• Some buyers feel the price is high relative to expectations, even though many praise the quality.

Specifications

Our Verdict

The Brooks Womens Glycerin 22 is a strong choice for anyone wanting maximum cushioning with a smooth ride and an accommodating fit. It shines for road running, cross training, and everyday comfort, and its medical certifications add value for those with foot health concerns. Pay attention to the cushioning level and price when comparing to lighter or more budget-focused alternatives.

Frequently Asked Questions

Are these shoes good for long runs?
Yes, the plush cushioning and stable platform make them comfortable for long road runs and recovery miles.

Do they provide arch support?
They are neutral by design but offer supportive cushioning; those needing extra support should consider a stability version like the Glycerin GTS 22.

Are they suitable for diabetic feet?
Yes, the Glycerin 22 is a certified PDAC A5500 diabetic shoe and carries the APMA Seal of Acceptance.