Brooks Womens Glycerin 22 Neutral Running Shoe - Plush (Style KB76)

In this review of the Brooks Womens Glycerin 22 Neutral Running Shoe the bottom line is simple: this is a neutral, highly cushioned road running shoe for women who prioritize plush comfort and smooth transitions. The reviewer found that the standout reason to buy is the updated DNA Tuned cushion, which creates soft landings in the heel and a more responsive toe-off. It also earns credibility for foot health with a PDAC A5500 diabetic certification and the APMA Seal of Acceptance, making it a reliable choice for runners or walkers seeking cushioning and supportive design without extra medial support.

Key Features

• Neutral support: Provides maximum cushioning while maintaining a neutral ride suitable for road running, gym sessions, and cross training.
• DNA Tuned cushion: Larger midsole cells in the heel deliver plush landings while smaller forefoot cells help with energetic toe-offs.
• Accommodating fit: The double jacquard knit upper stretches to fit different foot shapes while remaining breathable and durable.
• Smooth transitions: A broad platform and tuned heel-to-forefoot design stabilize the foot and encourage consistent heel-to-toe motion.
• Certified foot health: PDAC A5500 diabetic shoe certification and the APMA Seal of Acceptance offer added reassurance for foot care needs.

Who It's For

The Glycerin 22 is best for women who want maximum plush cushioning in a neutral running shoe and who value a soft, protective ride over aggressive responsiveness. It suits road runners, walkers who cover long distances, and gym users who prefer a soft underfoot feel.

Runners who need strong motion control or extra medial support should consider a stability model such as the Glycerin GTS line instead. Also, shoppers who expect a very snug, narrow fit may want to try these on first since customer feedback varies on sizing and some find them smaller than expected.

Pros & Cons

Pros

• Exceptional cushioning that reduces impact on knees and hips for long walks or runs.
• Comfortable, roomy toe box and breathable knit upper that improve fit and airflow.
• Stable, broad platform that smooths heel-to-toe transitions for a confident stride.

Cons

• Sizing can be inconsistent across customers, with some reporting that they run smaller than expected.

Specifications

Model	Glycerin 22
Support type	Neutral
Cushion technology	DNA Tuned midsole with dual-size cells
Upper	Double jacquard knit, breathable and flexible
Certifications	PDAC A5500 diabetic shoe, APMA Seal of Acceptance
Intended use	Road running, cross training, gym, walking

Our Verdict

The Brooks Womens Glycerin 22 is a strong buy for women seeking a neutral shoe with maximum cushioning and a smooth ride; its DNA Tuned midsole and roomy, breathable upper deliver comfortable long-distance wear and reliable support for everyday training. It represents good value for runners prioritizing comfort and foot health, though prospective buyers should confirm sizing before committing.

Frequently Asked Questions

Are these shoes good for long walks?
Yes. Customers report comfortable long-distance walking due to the soft heel landings and high level of cushioning.

Do these provide stability for overpronation?
No. The Glycerin 22 is a neutral shoe; those needing added support should look at stability versions like the Glycerin GTS.

How does the fit run?
Sizing feedback varies; some find them true to size while others say they run smaller, so trying them on or checking a size guide is recommended.