Brooks Womens Glycerin 22 Neutral Running Shoe - Plush (Style KVR6)

In this review of the Brooks Womens Glycerin 22 Neutral Running Shoe the bottom line is simple: this shoe is for runners and active women who want maximum cushioning without extra corrective support. The standout reason to buy is the updated DNA Tuned cushion, which blends larger heel cells for soft landings with smaller forefoot cells for responsive toe-offs, producing a noticeably smooth transition through each stride. Reviewers consistently praise the comfort, roomy toe box and padded heel, making it a reliable choice for road miles, gym sessions or long days on your feet.

Key Features

• DNA Tuned Cushion: Larger midsole cells in the heel deliver soft, plush landings while smaller forefoot cells support energetic toe-offs for a balanced ride.
• Neutral Support: Provides neutral stability with the maximum level of cushioning, ideal for runners who do not need corrective guidance.
• Accommodating Fit: The double jacquard knit upper stretches to fit a range of foot shapes while maintaining breathability and durability.
• Smooth Transitions: A broad platform and tuned heel and forefoot help stabilize the foot and promote smooth heel-to-toe motion.
• Medical Endorsements: Certified as a PDAC A5500 Diabetic shoe and bearing the APMA Seal of Acceptance, indicating attention to foot-health considerations.

Who It's For

The Glycerin 22 is best for women seeking plush cushioning for road running, cross training or all-day comfort. Its neutral design and generous padding suit runners with medium to low pronation who prioritize softness underfoot and a spacious toe area.

Those who need corrective stability or rigid motion control should look elsewhere, such as a support-focused model. If you prefer a minimalist, very low-profile shoe or need an extremely firm ride, the Glycerin 22's plush DNA Tuned midsole may feel too soft.

Pros & Cons

Pros

• Comfortable, plush cushioning that many customers describe as roomy in the toe and well-padded at the heel.
• Broad platform and tuned geometry offer stable, smooth transitions from heel to toe.
• Upper knit is breathable and accommodating, reducing pressure points for wider feet.
• Certified PDAC A5500 and APMA Seal reflect attention to foot health and diabetic-friendly fit.

Cons

• Some shoppers consider the price high relative to expectations, though many still call it good value for comfort.
• Neutral design means it is not ideal for runners needing added support or motion control.

Specifications

Model	Glycerin 22
Support Type	Neutral
Midsole Technology	DNA Tuned with dual-size cells
Upper	Double jacquard knit
Certifications	PDAC A5500 Diabetic shoe; APMA Seal of Acceptance
Predecessor	Glycerin 21

Our Verdict

The Brooks Womens Glycerin 22 is a strong choice for women who want maximum cushioning and a smooth ride without corrective support. It pairs a plush, responsive DNA Tuned midsole with an accommodating knit upper and sensible foot-health certifications, making it a worthwhile pick for road runners and the active everyday wearer who values comfort over rigid support.

Frequently Asked Questions

Are these shoes good for long runs?
Yes; the plush midsole and smooth transitions make them well suited to long road runs, especially for runners who prefer soft cushioning.

Do they fit wide feet?
The double jacquard knit upper is accommodating and customers report a roomy toe area, so they work well for many wider foot shapes.

Are these shoes supportive for overpronation?
No; the Glycerin 22 is a neutral shoe and those needing added stability should consider a support-specific model.