Brooks Womens Glycerin 22 Neutral Running Shoe - Plush (Style L1F9)

In this review of the Brooks Womens Glycerin 22 Neutral Running Shoe the bottom line is simple: if you want maximum plush cushioning with a smooth heel-to-toe ride, these are hard to beat. The Glycerin 22 uses Brooks DNA Tuned midsole cells to deliver soft landings in the heel and a more responsive forefoot for toe-offs, and it is one of the few road running shoes certified as a PDAC A5500 diabetic shoe and approved by the APMA. For runners and gym users seeking a neutral platform and roomy, comfortable fit, this shoe prioritizes comfort without sacrificing stability.

Key Features

• DNA Tuned Cushion: Larger midsole cells in the heel and smaller forefoot cells create plush landings and energetic toe-offs for smoother transitions.
• Neutral Support: The shoe provides a neutral platform with maximum cushioning, making it versatile for road running, cross training, or gym workouts.
• PDAC A5500 & APMA Approval: Certified as a diabetic-friendly shoe and granted the APMA Seal of Acceptance, signaling attention to foot health and fit.
• Accommodating Fit: A double jacquard knit upper offers flexibility and breathability while providing room in the toe box and a comfortable padded heel.
• Smooth Transitions: A broad platform plus a tuned heel and forefoot stabilizes the foot and smooths heel-to-toe movement.

Who It's For

The Glycerin 22 is best for recreational and dedicated road runners who prioritize cushioning and a smooth ride over aggressive responsiveness. It also suits walkers, gym-goers, and anyone needing a roomier toe box and a padded heel for long periods on their feet.

Runners who require significant corrective support or who prefer minimal, ultra-light race shoes should look elsewhere; if you need a stability model, consider the Glycerin GTS 22 for added support instead of this neutral version.

Pros & Cons

Pros

• Exceptional cushioning that keeps long runs comfortable without feeling overly mushy.
• Roomy, breathable upper and padded heel deliver a comfortable everyday fit and reduced hot spots.
• Certified PDAC A5500 and APMA accepted, useful for customers with foot health concerns.

Cons

• Some buyers may find the price higher than expected for a neutral trainer despite the premium cushioning.

Specifications

Model	Glycerin 22
Support type	Neutral
Midsole technology	DNA Tuned dual-size midsole cells
Upper	Double jacquard knit, breathable and flexible
Health certifications	PDAC A5500 diabetic shoe, APMA Seal of Acceptance
Predecessor	Glycerin 21

Our Verdict

The Brooks Glycerin 22 is an excellent choice for runners and active users who want maximum, reliable cushioning and a smooth, stable transition underfoot. Its accommodating knit upper and certified foothealth credentials add practical value, making it a recommended buy for anyone prioritizing comfort on runs, walks, or in the gym.

Frequently Asked Questions

Are these shoes good for long runs?
Yes. The plush DNA Tuned cushioning and broad platform make the Glycerin 22 comfortable for long road runs and extended wear.

Do they provide arch support?
The Glycerin 22 is a neutral shoe with moderate built-in support; customers report adequate arch comfort but those needing added support should choose a stability model.

Is the fit roomy?
The double jacquard knit upper creates an accommodating fit with extra room in the toe box and a padded heel to reduce rubbing.