Brooks Womens Glycerin 22 Neutral Running Shoe - Plush (Style PWMT)

In this review of the Brooks Womens Glycerin 22 Neutral Running Shoe the bottom line is simple: this shoe is for runners and active women who want maximum cushioning without extra corrective support. The Glycerin 22 stands out because of its DNA Tuned midsole design that blends larger heel cells for soft landings with smaller forefoot cells for lively toe-offs, delivering a plush yet responsive ride. It also carries certifications for foot health, making it a strong pick for anyone prioritizing comfort and a roomy, accommodating fit.

Key Features

• DNA Tuned Cushion: Larger midsole cells in the heel create soft, plush landings while smaller forefoot cells promote energetic and responsive toe-offs.
• Neutral Support: Designed as a neutral shoe, it provides maximum cushioning for road running, gym sessions, and everyday wear without added stability elements.
• Accommodating Fit: The double jacquard knit upper offers flexibility and breathability while allowing extra room in the toe box for comfort.
• Smooth Transitions: A broad platform with a tuned heel and forefoot helps stabilize the foot and smooth heel-to-toe transitions for an even stride.
• Health Certifications: Certified PDAC A5500 as a diabetic shoe and granted the APMA Seal of Acceptance, indicating attention to foot health and fit.

Who It's For

The Glycerin 22 is best for neutral road runners, gym-goers, and anyone who prioritizes cushioning and comfort over corrective stability. Women who appreciate a roomy toe box, padded heel, and breathable knit upper will find this shoe especially appealing during longer runs or all-day wear.

Those who need strong motion control or pronounced support for overpronation should look at stability models instead, such as the Glycerin GTS line, which offers the same cushioning with added guidance. If minimal or ultra-light racing shoes are preferred, the Glycerin 22 is heavier and geared toward comfort rather than speed.

Pros & Cons

Pros

• Exceptional cushioning that balances plush landings with responsive toe-offs thanks to the DNA Tuned design.
• Comfortable, accommodating fit with a breathable double jacquard knit upper and roomy toe area.
• Broad platform and tuned geometry provide stable, smooth transitions from heel to toe.
• Certified for foot health with PDAC A5500 classification and the APMA Seal of Acceptance.

Cons

• Higher price may be a downside for some shoppers who find the cost heavier than expected.
• Not intended for runners who require firm motion control or minimal racing shoes.

Specifications

Model	Glycerin 22
Support Type	Neutral
Midsole Technology	DNA Tuned dual-size cell cushioning
Upper	Double jacquard knit, breathable and flexible
Use	Road running, cross training, gym, everyday
Health Certifications	PDAC A5500 diabetic shoe; APMA Seal of Acceptance

Our Verdict

The Brooks Womens Glycerin 22 is an excellent choice for women who want maximum cushioning and a comfortable, roomy fit for road running and daily wear. Its DNA Tuned midsole balances plush landings with responsive toe-offs, and the health certifications add confidence for sensitive feet. While it is pricier and not aimed at runners needing corrective support, it represents strong value for comfort-focused athletes and walkers.

Frequently Asked Questions

Are these shoes good for long runs?
The plush cushioning and stable platform make the Glycerin 22 well suited to long runs and extended wear.

Do they provide arch support?
They are neutral shoes that offer cushioning and general support but not the added corrective arch support of a stability model.

Is the fit roomy?
Yes, customers report a roomy toe box and an accommodating knit upper that provides comfort without pinching.