Brooks Womens Glycerin 22 Neutral Running Shoe - Soft Cushioned Fit

In this review of the Brooks Womens Glycerin 22 Neutral Running Shoe the bottom line is simple: this is a plush, well-cushioned daily trainer best suited for women who prioritize comfort and joint support during long walks or easy runs. The standout is the DNA Tuned Nitro-Infused foam that delivers a soft, squishy ride without feeling flat, while the engineered double jacquard mesh upper provides a breathable, secure fit. Customers repeatedly cite comfort, support for knees and hips, and roomy toe box as the main reasons they keep reaching for these shoes.

Key Features

• DNA Tuned Nitro-Infused foam: provides a noticeably soft and responsive midsole that cushions long distances and reduces impact on knees and hips.
• Engineered double jacquard mesh upper: offers breathability and a conforming fit that keeps the foot secure without excessive pressure.
• Roomy toe box: allows natural toe splay and improves comfort on longer walks or runs where feet swell slightly.
• Supportive midsole geometry: helps stabilize the foot for a neutral stride while still feeling plush underfoot.
• Style-forward design: delivers a clean athletic look that customers say works for both workouts and casual wear.

Who It's For

The Brooks Womens Glycerin 22 is ideal for women who want maximum cushioning and joint protection for walking, recovery runs, or everyday wear. Runners who favor a soft, plush ride and need solid support for knees and hips will appreciate its construction and cushioning technology.

Those who prefer a very firm, performance-oriented race shoe or require exact half-size precision should look elsewhere, since some customers report inconsistent sizing and a perception that the shoe runs small. If minimal weight and a razor-sharp responsiveness are priorities, a lighter racer would be a better match.

Pros & Cons

Pros

• Exceptional cushioning that reduces impact and keeps long walks comfortable.
• Supportive feel around the midfoot and heel that aids knee and hip comfort.
• Breathable engineered mesh upper that balances structure and airflow.
• Roomy toe box for natural foot movement and less pressure on toes.

Cons

• Sizing appears inconsistent for some customers, with reports that the shoe can run small.
• Its plush, squishy ride may feel too soft for runners seeking a firmer, race-ready shoe.

Specifications

Brand	Brooks
Model	Glycerin 22
Gender	Womens
Cushioning	DNA Tuned Nitro-Infused foam
Upper	Engineered double jacquard mesh
Fit notes	Roomy toe box; some customers report sizing runs small

Our Verdict

The Glycerin 22 is a strong choice for women seeking plush cushioning and reliable joint support in a neutral trainer. It pairs a soft Nitro-infused midsole with a breathable mesh upper to create comfortable daily shoes that handle long walks and recovery runs well. Consider sizing carefully, but if comfort and cushioning matter most, this shoe offers good value.

Frequently Asked Questions

Do these shoes run true to size?
Some customers report the Glycerin 22 runs small, so trying on or ordering a half size up may be wise if you are between sizes.

Are these shoes good for long distances?
Yes; the DNA Tuned Nitro-Infused foam and roomy toe box make them suitable for long walks and easy runs where cushioning is a priority.

Is the upper breathable?
The engineered double jacquard mesh upper provides good breathability while maintaining a secure, comfortable fit.