Brooks Womens Glycerin GTS 22 Supportive Running Shoe - Cushioned bay
Brooks Womens Glycerin GTS 22 Supportive Running Shoe - Cushioned bay
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In this review the Brooks Womens Glycerin GTS 22 stands out as a daily trainer for runners and walkers who need plush cushioning plus corrective support. The biggest reason to consider these shoes is the combination of DNA Tuned cushion for soft landings and the GuideRails support system that keeps excess motion under control, making transitions smooth without feeling overly rigid. Reviewers praise the comfort and arch support, and the shoe's diabetic-friendly certification is a meaningful bonus for people who need it.
Key Features
- GuideRails support: Helps stabilize the foot by limiting excess motion so runs and gym sessions feel more controlled.
- DNA Tuned cushion: Larger heel cells give plush landings while smaller forefoot cells provide responsive toe-offs for smoother strides.
- Accommodating knit upper: The double jacquard knit delivers flexibility and breathability while maintaining a secure fit.
- Broad platform: A wider base stabilizes the foot and promotes smooth heel-to-toe transitions on pavement and treadmills.
- Diabetic-friendly certification: Certified PDAC A5500, offering reassurance for customers who require medical-grade footwear features.
Who It's For
The Glycerin GTS 22 is best for neutral to mild overpronators who want a plush, supportive daily trainer for road running, gym work, and long walks. It suits runners who prioritize cushioning and a stable ride over ultra-light speed work.
Runners who want a very narrow racing fit or minimal, barefoot-style feel should look elsewhere, as the shoe emphasizes cushioning and support rather than aggressive responsiveness or extreme lightness.
Pros & Cons
Pros
- Exceptional comfort and cushioning that customers describe as life-changing for long runs and standing workdays.
- Reliable support from GuideRails keeps excess motion in check for a stable stride.
- Quality construction and stylish, subtle colorways that get positive comments from owners.
- Certified PDAC A5500 for diabetic-friendly use, which is rare among everyday trainers.
Cons
- Some customers report the toe box can feel narrow, so those with wide forefeet may need to size up or try alternate models.
- Not aimed at racers seeking a lightweight, highly responsive shoe.
Specifications
| Model | Glycerin GTS 22 |
| Support System | GuideRails holistic support |
| Cushioning | DNA Tuned midsole with dual-size cells |
| Upper | Double jacquard knit, breathable and flexible |
| Platform | Broad platform for stable transitions |
| Use | Road running, cross training, gym |
| Certification | PDAC A5500 diabetic shoe |
Our Verdict
The Brooks Womens Glycerin GTS 22 is a strong choice for runners and active walkers who want plush cushioning plus built-in support to control excess motion. It delivers quality construction, a comfortable ride, and diabetic-friendly certification, making it good value for anyone prioritizing comfort and stability over lightweight speed.
Frequently Asked Questions
Do these run true to size?
Fit feedback is mixed; many find their normal size fits well but some report a narrow toe box and may prefer to try a half size up if possible.
Are they good for daily road running?
Yes, the balanced cushion and GuideRails support make them well suited to daily road runs and mixed training.
Is this shoe suitable for diabetic foot care?
Yes, the Glycerin GTS 22 is certified PDAC A5500, indicating it meets standards for diabetic-friendly footwear.
Editor's Take
The Glycerin GTS 22 combines plush DNA Tuned cushioning with GuideRails support for stable, comfortable road running and daily training, making it a strong choice for runners who prioritize comfort and control.

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