Brooks Womens Glycerin GTS 22 Supportive Running Shoe - Cushioned Fit

In this review of the Brooks Womens Glycerin GTS 22 Supportive Running Shoe, the bottom line is clear: this shoe is for women seeking plush cushioning with guided stability for road running and everyday training. The single biggest reason to buy is the combination of DNA Tuned cushioning and GuideRails support, which together deliver a soft, responsive ride while keeping excess motion under control. Reviewers who prioritize comfort, arch support and smooth transitions will find these shoes immediately appealing.

Key Features

• GuideRails Support: The holistic GuideRails system keeps excess motion in check so the foot moves along a natural path without sacrificing comfort.
• DNA Tuned Cushion: Dual-size midsole cells provide plush landings in the heel and responsive toe-offs in the forefoot to smooth heel-to-toe transitions.
• PDAC A5500 Certified: Built as a certified diabetic-friendly shoe, offering an accommodating platform for sensitive feet.
• Accommodating Fit: The double jacquard knit upper stretches where needed for breathability while holding its shape for lasting fit and durability.
• Broad Stable Platform: A wider base stabilizes the foot during runs and cross training for more confidence on road surfaces.

Who It's For

The Glycerin GTS 22 is best for runners and active women who want a plush, supportive daily trainer for road running, gym sessions, and walking. It suits people who appreciate a soft heel landing paired with a responsive forefoot and those who benefit from the GuideRails system for added stabilization.

It may be less ideal for ultra-light racers who prioritize minimal weight or for runners who need a very wide toe box, as some users note a slightly narrow forefoot feel. Those seeking a maximalist, rockered ride should also look elsewhere.

Pros & Cons

Pros

• Exceptional comfort and cushioning that many users describe as life-changing for long runs and daily wear.
• Reliable support from GuideRails helps control excess motion without feeling restrictive.
• Durable, breathable knit upper offers an accommodating fit and clean styling choices.
• Certified PDAC A5500 diabetic-friendly construction for sensitive feet.

Cons

• Some customers find the toe box a touch narrow, which can be an issue for wider forefeet.
• Perceived value varies; a few users question the price relative to other trainers.

Specifications

Brand	Brooks
Model	Glycerin GTS 22
Intended Use	Road running, cross training, gym
Support System	GuideRails holistic support
Midsole Technology	DNA Tuned dual-cell cushioning
Upper	Double jacquard knit for fit and breathability
Certification	PDAC A5500 diabetic-friendly

Our Verdict

The Brooks Womens Glycerin GTS 22 is a strong choice for women who want plush, stable cushioning and dependable support for daily miles. Its combination of DNA Tuned cushioning and GuideRails makes it a solid value for runners who prioritize comfort and controlled motion, though those needing extra toe-box width should try them on first.

Frequently Asked Questions

Do these run true to size?
Fit varies among customers; many find their usual size comfortable, but some report a slightly narrow toe box so trying them on is recommended.

Are they suitable for long road runs?
Yes. The DNA Tuned midsole and broad platform provide plush landings and smooth transitions ideal for longer road sessions.

Can people with diabetes wear these?
Yes. The Glycerin GTS 22 is PDAC A5500 certified, making it a good option for diabetic foot care needs.