Brooks Womens Glycerin GTS 22 Supportive Running Shoe - Cushioned Road

Our review of the Brooks Womens Glycerin GTS 22 finds it best suited to runners and gym-goers who prioritize plush cushioning and guided stability. The single biggest reason to consider these shoes is the combination of the new DNA Tuned midsole and GuideRails support, which together create exceptionally smooth heel-to-toe transitions while keeping excess motion under control. They feel noticeably softer than the previous model yet maintain a broad, stable platform that makes longer road runs and daily training sessions easier on the legs.

Key Features

• DNA Tuned Cushion: Larger midsole cells in the heel and smaller cells in the forefoot deliver a soft landing and a responsive toe-off for smoother runs.
• GuideRails Support: Holistic support keeps excess motion in check for more stable foot tracking during distance runs and cross training.
• Accommodating Fit: The double jacquard knit upper stretches where needed and breathes well while holding shape for comfortable long wear.
• Smooth Transitions: A broad platform combined with a tuned heel and forefoot helps stabilize the foot and smooth the gait cycle.
• Certified Diabetic Friendly: The Glycerin GTS 22 is PDAC A5500 certified, making it appropriate for runners who need diabetic shoe features.

Who It's For

The Glycerin GTS 22 is ideal for women who want plush cushioning with built-in stability-road runners, gym regulars, and anyone who appreciates a soft landing without sacrificing control. Its supportive GuideRails system and broad sole suit mild overpronators and those who want extra reassurance on longer outings.

Those who need an extra-wide toe box or prefer a very narrow racing fit should look elsewhere; some users report the toe area can feel snug. If you want a minimalist or ultra-lightweight racing shoe, this heavily cushioned, supportive trainer is not the right choice.

Pros & Cons

Pros

• Exceptional cushioning from DNA Tuned that balances plush landings with responsive toe-offs.
• Effective GuideRails support that limits excess motion and aids stability during long runs.
• Breathable, flexible double jacquard knit upper that adapts to the foot for comfort.
• PDAC A5500 certification makes it suitable for diabetic customers needing supportive footwear.

Cons

• The toe box can feel narrow for some customers, so sizing and fit checks are recommended.
• Heavier and more cushioned than dedicated racing shoes, so not ideal for speed-focused runners.

Specifications

Brand	Brooks
Model	Glycerin GTS 22
Support System	GuideRails holistic support
Midsole Technology	DNA Tuned with dual-size cells
Upper	Double jacquard knit for flexibility and breathability
Use Case	Road running, cross training, gym
Certification	PDAC A5500 diabetic shoe

Our Verdict

The Brooks Glycerin GTS 22 is a strong choice for women who want luxurious cushioning plus trustworthy stability for everyday runs and workouts. Its DNA Tuned midsole and GuideRails support offer a balanced ride that helps reduce strain over longer distances, making it good value for runners who prioritize comfort and injury-aware support.

Frequently Asked Questions

Are these shoes good for overpronation?
Yes, the GuideRails support is designed to limit excess motion and is helpful for mild overpronation without feeling intrusive.

Do they run true to size?
Customers disagree; some find the fit true to size while others report the toe box feels narrow, so try them on if possible.

Can I use these for gym workouts?
Yes, the stable platform and cushioned midsole make them suitable for gym sessions, cross training, and road running.