Brooks Womens Glycerin GTS 22 Supportive Running Shoe - Plush

In this review the Brooks Womens Glycerin GTS 22 makes a clear case for runners and walkers who prioritize maximum cushioning with dependable stability. The biggest reason to consider these shoes is the DNA Tuned midsole that blends larger heel cells and smaller forefoot cells for soft landings and energetic toe-offs, creating a plush yet responsive ride. They also arrive with PDAC A5500 diabetic certification and the APMA Seal of Acceptance, which reinforces their design focus on comfort and foot health.

Key Features

• DNA Tuned Cushion: Larger midsole cells in the heel provide soft, plush landings while smaller cells in the forefoot help deliver responsive toe-offs for smoother strides.
• Neutral Support: Offers a neutral platform with maximum cushioning that suits road running, gym sessions, and everyday wear without forcing excessive motion control.
• Accommodating Fit: A double jacquard knit upper flexes with the foot for breathability and a more forgiving fit across the forefoot and midfoot.
• Smooth, Stable Transitions: A broad platform combined with a tuned heel and forefoot stabilizes the foot and smooths heel-to-toe transitions during runs.
• Medical and Quality Seals: Certified PDAC A5500 as a diabetic shoe and awarded the APMA Seal, indicating attention to foot health and construction quality.

Who It's For

The Glycerin GTS 22 is best for women who want luxurious cushioning with a stable ride: long-distance road runners who favor plush shock absorption, walkers seeking comfort on hard surfaces, and gym users who want a soft but steady platform. The certified diabetic fit also makes these shoes appealing to buyers prioritizing foot health and pressure relief.

Those who prefer a very wide toe box or a minimalist, low-drop shoe should look elsewhere; some customers report a narrower toe area and the shoe is built around cushioning rather than a barefoot feel. If nimble speed work or trail grip are your main priorities, a lighter, more responsive trainer or trail-specific shoe will serve better.

Pros & Cons

Pros

• Exceptional cushioning and comfortable arch support for long runs and all-day wear.
• Stable, broad platform and tuned transitions reduce foot fatigue over distance.
• Accommodating knit upper improves breathability and overall fit comfort.

Cons

• Some users find the toe box too narrow, so those needing extra forefoot width may have fit issues.
• Heavily cushioned design may feel bulky for runners seeking a minimal, fast shoe.

Specifications

Brand	Brooks
Model	Glycerin GTS 22
Support Type	Neutral support with tuned stability
Midsole Technology	DNA Tuned with dual-size cells
Upper	Double jacquard knit
Certifications	PDAC A5500 diabetic shoe; APMA Seal of Acceptance

Our Verdict

The Glycerin GTS 22 is a strong choice for women who want maximum cushioning without sacrificing stability; its DNA Tuned midsole and broad platform create a comfortable, secure ride for road running, walking, and everyday use. It represents good value for buyers prioritizing comfort and foot health, though those needing a very wide toe box or a lightweight racer should consider alternatives.

Frequently Asked Questions

Are these shoes good for long road runs?
Yes. The plush DNA Tuned cushioning and stable platform make them well suited to longer road sessions and high-mileage training.

Do they work for people with diabetic foot concerns?
They are certified PDAC A5500 and have the APMA Seal, indicating they meet standards for accommodating diabetic foot needs and general foot health.

Do they run true to size?
Customer feedback is mixed; some find the fit true to size while others note the toe box can feel narrow, so trying them on or checking return options is advised.