Brooks Womens Glycerin GTS 22 Supportive Running Shoe - Plush Clothing

In this review the Brooks Womens Glycerin GTS 22 stands out as a cushioned, supportive road running shoe for women who prioritize comfort and stability. The biggest reason to buy is the combination of Brooks' DNA Tuned midsole and GuideRails support, which delivers plush landings and controlled motion that suit longer runs or daily training. The shoe also serves as a stable option for cross training or gym work while offering an accommodating knit upper for breathability and a broad platform for smooth transitions.

Key Features

• DNA Tuned cushion: Larger midsole cells in the heel give soft, plush landings while smaller forefoot cells help energetic toe-offs for a balanced ride.
• GuideRails support: A holistic support system keeps excess motion in check so the foot and knee stay aligned through each stride.
• Accommodating fit: The double jacquard knit upper stretches where needed for comfort and breathability without feeling flimsy.
• Stable platform: A broad sole base stabilizes the foot and smooths heel-to-toe transitions for a confident feel on road surfaces.
• Diabetic-friendly option: The Glycerin GTS 22 is a certified PDAC A5500 diabetic shoe, offering an accommodating last for special-fit needs.

Who It's For

The Glycerin GTS 22 is ideal for women who want maximum cushioning with added support; long-distance recreational runners and walkers who appreciate a plush ride will like the DNA Tuned midsole and GuideRails stability. It also works well for gym sessions or cross training where joint protection and a stable platform matter.

Runners who prefer a very roomy toe box or a minimalist, responsive feel should look elsewhere, as some wearers report a narrower toe area and this shoe leans toward soft cushioning rather than a race-day crispness.

Pros & Cons

Pros

• Exceptional cushioning and smooth transitions from the tuned midsole.
• GuideRails system provides reliable stabilization for excess motion.
• Breathable, durable knit upper that adapts to the foot for comfort.
• Certified PDAC A5500 diabetic shoe for users needing an accommodating fit.

Cons

• Some customers find the toe box narrower than expected, so width-conscious shoppers should try them on first.
• Heavier cushioning means the shoe is less suited to fast, race-pace efforts.

Specifications

Model	Glycerin GTS 22
Support system	GuideRails holistic support
Midsole technology	DNA Tuned with varied cell sizes
Upper	Double jacquard knit, breathable and flexible
Primary use	Road running, cross training, gym
Special certification	PDAC A5500 diabetic shoe

Our Verdict

The Brooks Womens Glycerin GTS 22 is a strong choice for women seeking plush cushioning plus thoughtful support; it excels for daily training, long runs, and anyone needing joint-friendly cushioning. While not the best option for racers or those needing an extra-wide toe box, its balanced ride and stabilization make it good value for runners prioritizing comfort and protection.

Frequently Asked Questions

Are these shoes good for long runs?
Yes, the DNA Tuned midsole and broad platform make them comfortable for longer road runs by smoothing transitions and reducing impact.

Do they provide arch and motion support?
Yes, the GuideRails system helps control excess motion and offers notable arch and overall stability for many users.

Do they run true to size?
Fit varies: some wearers find them true to size, while others report a slightly narrow toe box, so trying them on is recommended.