Brooks Womens Glycerin GTS 22 Supportive Running Shoe - Plush Road

In this review the Brooks Womens Glycerin GTS 22 emerges as a cushioned, supportive option for runners and walkers who prioritize plush landings and controlled motion. The single biggest reason to consider these shoes is the combination of the DNA Tuned cushioning that balances soft heel impact with responsive toe-offs and the GuideRails support system that limits excess movement, making them feel secure during road miles or gym sessions. Fit and toe box width vary among users, but many praise the comfort and stability these deliver for daily training.

Key Features

• GuideRails support: Helps stabilize the foot by keeping excess motion in check so runs and cross training sessions feel more controlled.
• DNA Tuned cushion: Dual-size midsole cells create a plush heel landing and a responsive forefoot for smoother transitions.
• Accommodating knit upper: The double jacquard knit offers breathability and a flexible fit that adapts to the foot for long wear.
• Broad platform: A wider base improves stability and supports a more stable heel-to-toe roll on road runs.
• Certified diabetic option: The shoe is PDAC A5500 certified, making it suitable for wearers who need diabetic-friendly footwear.

Who It's For

The Glycerin GTS 22 is best for women who want a high level of cushioning without sacrificing support, including road runners who favor long, comfortable miles, gym users who need stable footwear for mixed workouts, and walkers seeking an easygoing daily trainer. Runners with mild overpronation will appreciate the GuideRails system that keeps motion controlled.

Those who should look elsewhere include runners who prefer extremely narrow, performance racing fits or minimal, low-drop shoes; the Glycerin GTS 22 prioritizes plush cushioning and stability over lightweight racing speed. Also, buyers seeking a very wide toe box should try these on first, as some users note a snuger toe area.

Pros & Cons

Pros

• Exceptional long-run comfort from the DNA Tuned midsole cushioning.
• Reliable stabilization from the GuideRails system for controlled motion.
• Comfortable, breathable fit thanks to the double jacquard knit upper.
• PDAC A5500 certification makes it suitable for diabetic-friendly use.

Cons

• Some wearers report the toe box feels a bit narrow, so fit can be inconsistent across foot shapes.
• Heavier and more cushioned than minimalist trainers, which may not suit speed-focused runners.

Specifications

Our Verdict

The Brooks Glycerin GTS 22 is a strong choice for runners and active walkers who want luxurious cushioning paired with guided support. Its DNA Tuned midsole and GuideRails system create comfortable, stable transitions that justify the investment for daily trainers and those needing a diabetic-certified option, though shoppers with very wide forefeet or a taste for lightweight race flats should try on for fit before buying.

Frequently Asked Questions

Do these run true to size?
Fit varies; many find true to size, but some report the toe box feels narrow so trying them on is recommended.

Are these good for long runs?
Yes, the generous cushioning and stable platform make them well suited to long road miles and recovery runs.

Is this shoe supportive for overpronation?
Yes, the GuideRails support system is designed to limit excess motion and help stabilize the foot during runs.