Brooks Womens Glycerin GTS 22 Supportive Running Shoe - Plush, Stable
Brooks Womens Glycerin GTS 22 Supportive Running Shoe - Plush, Stable
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In this review the Brooks Womens Glycerin GTS 22 Supportive Running Shoe stands out as a plush, stable option for women who prioritize cushioning and smooth transitions. The single biggest reason to buy is the updated DNA Tuned cushioning, which blends larger heel cells for soft landings with smaller forefoot cells for responsive toe-offs, delivering both comfort and forward propulsion on road runs and daily training. It also carries PDAC A5500 diabetic certification and the APMA Seal of Acceptance, which adds confidence for walkers and runners seeking foot-friendly design.
Key Features
- DNA Tuned Cushion: Larger midsole cells in the heel and smaller cells in the forefoot create a balance of plush impact protection and energetic toe-offs for smoother strides.
- Neutral Support: Delivers maximum cushioning while maintaining a neutral platform suitable for road running, gym workouts, and cross training.
- Accommodating Fit: A newly engineered double jacquard knit upper provides breathable stretch and durability to reduce hot spots during long wear.
- Stable Transitions: A broad platform with a tuned heel and forefoot stabilizes the foot and smooths heel-to-toe movement for confident pace changes.
- Medical Acceptance: Certified as a PDAC A5500 diabetic shoe and granted the APMA Seal of Acceptance, supporting foot health for sensitive users.
Who It's For
The Glycerin GTS 22 is best for runners and walkers who want maximum cushioning without sacrificing responsiveness, and for anyone who benefits from an APMA-accepted, diabetic-certified shoe. It suits road runners, gym-goers, and people who log long miles and need protection from impact.
Runners with very wide feet should try them on first, as some customers find the fit snug despite the knit upper. Those seeking a minimalist, low-cushion shoe or a heavy motion-control ride should look elsewhere.
Pros & Cons
Pros
- Exceptional cushioning that many users describe as noticeably comfortable for long runs and daily wear.
- Supportive, stable platform that smooths transitions and reduces stress on hips and back for some wearers.
- Breathable knit upper that offers an accommodating fit and reduces rubbing during extended use.
Cons
- Fit can feel too snug for some with wide feet, so sizing or width options may be necessary.
- Value perceptions are mixed among customers; some feel the price matches performance while others are less certain.
Specifications
| Brand | Brooks |
| Model | Glycerin GTS 22 |
| Support | Neutral support with enhanced cushioning |
| Midsole Technology | DNA Tuned with dual-size cells |
| Upper | Double jacquard knit, breathable and accommodating |
| Certifications | PDAC A5500 diabetic shoe, APMA Seal of Acceptance |
Our Verdict
The Glycerin GTS 22 is a strong pick for runners and walkers who want maximum cushioning with smooth, stable transitions and medically recognized foot-friendly features. Try them if you value plush impact protection and responsiveness; however, test the fit if you have wide feet to ensure comfort over long distances.
Frequently Asked Questions
Are these shoes good for long road runs?
Yes; the DNA Tuned midsole and broad platform provide plush cushioning and stable heel-to-toe transitions suited to extended road runs.
Do they fit true to size?
Many customers report a true-to-size fit, but some with wide feet find them tight, so consider trying a wider size or half size up if you are between sizes.
Are these shoes appropriate for people with sensitive feet?
Yes; the PDAC A5500 diabetic certification and APMA Seal indicate they are designed with foot health and comfort in mind.
Editor's Take
The Glycerin GTS 22 delivers plush DNA Tuned cushioning, stable heel-to-toe transitions, and medical certifications that make it a great choice for runners and walkers who want maximum comfort and foot-friendly design; try a wider size if you have wide feet.

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