Brooks Womens Glycerin GTS 22 Supportive Running Shoe - Smooth balance

In this review of the Brooks Womens Glycerin GTS 22 Supportive Running Shoe the bottom line is straightforward: this is a cushioned, stability-focused road shoe for women who prioritize plush landings and guided motion. The single biggest reason to consider the Glycerin GTS 22 is its combination of Brooks DNA Tuned midsole and GuideRails support, which together deliver luxurious cushioning with controlled transitions for runners, gym users, or anyone seeking extra stability in everyday wear.

Key Features

• DNA Tuned Cushion: Larger midsole cells in the heel and smaller cells in the forefoot provide soft, plush landings and responsive toe-offs for smoother gait transitions.
• GuideRails Support: The holistic GuideRails system keeps excess motion at bay to stabilize the foot and protect knees during longer runs or mixed workouts.
• Accommodating Fit: The double jacquard knit upper stretches to fit a variety of foot shapes while remaining breathable and durable for regular use.
• Broad Platform: A wider base stabilizes the foot to promote steady heel-to-toe movement and reduce wobble on road surfaces.
• Certified Diabetic Option: The Glycerin GTS 22 is a certified PDAC A5500 diabetic shoe, making it suitable for users who need therapeutic footwear.

Who It's For

The Glycerin GTS 22 is ideal for runners and active women who want maximum cushioning combined with guidance to limit excess motion; it works well for road running, cross training, gym sessions or long days on your feet. The supportive GuideRails make it a good pick for those with mild overpronation who still want a soft, plush ride rather than a firm stability shoe.

Those who prefer a very wide toe box or minimalist, low-profile shoes should look elsewhere, as some users report a narrower toe area and the shoe emphasizes cushioning and stability over minimal feel or racing performance.

Pros & Cons

Pros

• Outstanding cushioning that many customers describe as life-changing for long miles and daily wear.
• Effective support from the GuideRails system that reduces excess motion without feeling overly intrusive.
• Comfortable, breathable knit upper that balances durability and a flexible, accommodating fit.

Cons

• Some users find the toe box too narrow, so fit can vary and trying on is recommended.
• Perceived value varies among buyers; a few customers question whether the price matches their expectations.

Specifications

Our Verdict

The Brooks Glycerin GTS 22 is a strong choice for women seeking plush, protective cushioning paired with stability features. It delivers exceptionally comfortable landings and guided motion that suit road runners and active users who prioritize comfort and support; just confirm fit if you need extra toe-room.

Frequently Asked Questions

Are these shoes good for overpronation?
The GuideRails system offers targeted support to limit excess motion, making the shoe suitable for mild to moderate overpronation.

Do they run true to size?
Customer experiences vary; some find the fit true to size while others report a slightly narrow toe box, so trying them on is recommended.

Can I use them for the gym and road running?
Yes, the design balances cushioning and stability, so they perform well for road runs, cross training and gym sessions.