Brooks Womens Glycerin GTS 22 Supportive Running Shoe - Smooth blends
Brooks Womens Glycerin GTS 22 Supportive Running Shoe - Smooth blends
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In this review the Brooks Womens Glycerin GTS 22 is presented as a plush, stability-focused road shoe best for runners who prioritize cushioning and controlled motion. The single biggest reason to buy is the combination of the updated DNA Tuned cushion and GuideRails support that work together to deliver soft landings and smoother toe-offs while limiting excess movement. The shoe balances a luxurious feel with purposeful stability, making it a clear choice for long miles, recovery runs, and anyone needing extra support without heavy, restrictive structure.
Key Features
- GuideRails support: Keeps excess motion at bay by guiding the foot along its natural path for steadier strides and reduced joint strain.
- DNA Tuned cushion: Larger midsole cells in the heel provide soft landings while smaller forefoot cells return energy for responsive toe-offs.
- Accommodating fit: The double jacquard knit upper stretches where needed and breathes well for a comfortable, secure feel across the foot.
- Smooth transitions: A broad platform plus a tuned heel and forefoot create stable, heel-to-toe roll for more confident road running.
- Certified diabetic option: The Glycerin GTS 22 is PDAC A5500 certified, making it suitable for runners who need a medical-grade accommodative shoe.
Who It's For
The Glycerin GTS 22 is ideal for women who want maximum cushioning with meaningful stability: long-distance road runners, those recovering from higher-impact training, and runners who prefer a plush ride without sacrificing control. It also suits gym-goers and cross-training athletes who like a cushioned platform that still limits overpronation.
Runners seeking a very narrow, racing-style fit or a minimalist, low-drop trainer should look elsewhere, as some users note the toe box can feel snug and the overall design favors cushioning and support over minimalist responsiveness.
Pros & Cons
Pros
- Outstanding comfort from a plush midsole that handles long miles well.
- Effective support via GuideRails to reduce excess motion and offer stable strides.
- Breathable, flexible upper that creates an accommodating fit for many foot shapes.
Cons
- Some users report the toe box can feel a bit narrow, so those needing wide forefoot room may need to size or fit-check carefully.
Specifications
| Brand | Brooks |
| Model | Glycerin GTS 22 |
| Support system | GuideRails holistic support |
| Cushioning | DNA Tuned midsole with varied cell sizes |
| Upper | Double jacquard knit, breathable and flexible |
| Best for | Road running, cross training, gym |
| Certification | PDAC A5500 diabetic certified |
Our Verdict
The Brooks Glycerin GTS 22 is a strong choice for runners who want a plush, stable shoe that reduces excess motion without feeling bulky. Its cushioning and support deliver comfort on long runs and daily training, and the accommodating knit upper improves fit for many wearers. Consider it good value if cushioning and guided stability are your priorities; shoppers needing extra toe-box width should try them on first.
Frequently Asked Questions
Do these run true to size?
Fit varies: many find them true to size, but some users report a narrow toe box so try for a fit check if you have a wider forefoot.
Are they good for long runs?
Yes, the DNA Tuned cushioning and broad platform make them comfortable and stable for extended road miles.
Can they be used for cross training?
Yes, they work well for gym sessions and cross training where cushioning and guided support are helpful.
Editor's Take
The Brooks Glycerin GTS 22 pairs plush DNA Tuned cushioning with GuideRails support to deliver a comfortable, stable ride for long road runs and daily training; try them on if you need extra toe-box width.

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