Brooks Womens Glycerin GTS 22 Supportive Running Shoe - Smooth Jewelry

In this review of the Brooks Womens Glycerin GTS 22 Supportive Running Shoe the bottom line is simple: this shoe is for women who want plush cushioning plus motion control in a comfortable daily trainer. The standout reason to buy is the combination of DNA Tuned cushion that blends plush landings with lively toe-offs and the GuideRails support system that keeps excess motion in check, making it an appealing choice for road running, gym work and everyday wear for runners who need stability without a heavy feel.

Key Features

• GuideRails support: A holistic support system controls excess motion to stabilize the foot and reduce strain on knees and hips during runs or cross training.
• DNA Tuned cushion: Dual-size midsole cells provide softer landings in the heel and responsive toe-offs for smoother transitions through each stride.
• Accommodating fit: The double jacquard knit upper delivers flexible stretch and breathable durability to reduce hot spots and adapt to varying foot shapes.
• Smooth, stable transitions: A broad platform and tuned heel-to-toe geometry stabilize the foot and promote fluid heel-to-toe motion.
• Certified diabetic option: This model is a PDAC A5500 certified diabetic shoe, offering an option for those needing medically recognized footwear.

Who It's For

The Glycerin GTS 22 is best for women who want serious cushioning combined with support: road runners who overpronate slightly, gym-goers who want stable trainers, and anyone who values long-run comfort thanks to the plush DNA Tuned midsole. The GuideRails system makes it useful for runners who have experienced knee, hip or back discomfort and want a shoe that keeps motion controlled.

This shoe is less well suited to racers or speed-focused runners who prioritize minimal weight and maximal responsiveness, and those who require a very wide toe box should try them on first, as customer feedback on toe space is mixed.

Pros & Cons

Pros

• Exceptional cushioning that balances soft landings with responsive toe-offs.
• Consistent support from the GuideRails system that helps stabilize the entire gait.
• Breathable, accommodating knit upper that adapts to the foot for comfort.

Cons

• Fit can be mixed across users; some may find the toe box narrow and should size or try before committing.

Specifications

Brand	Brooks
Model	Glycerin GTS 22
Support System	GuideRails holistic support
Midsole Technology	DNA Tuned dual-cell cushioning
Upper	Double jacquard knit, breathable and flexible
Best Use	Road running, cross training, gym, daily wear
Medical Certification	PDAC A5500 diabetic shoe certified

Our Verdict

The Brooks Womens Glycerin GTS 22 is a strong choice for women who want plush, stable trainers that reduce excess motion without feeling clunky. It represents good value for runners who prioritize comfort and injury-conscious support, though those needing a very wide toe box or racing flats should consider alternatives.

Frequently Asked Questions

Are these shoes good for overpronation?
Yes, the GuideRails support system helps control excess motion and is suited to mild to moderate overpronation.

Do they feel heavy on long runs?
No, most users find the Glycerin GTS 22 balances plush cushioning with a stable, not overly heavy, platform for long runs.

Are they suitable for diabetic feet?
Yes, this model is PDAC A5500 certified as a diabetic shoe, making it suitable for users who need medically recognized accommodations.