Brooks Womens Glycerin GTS 22 Supportive Running Shoe - Smooth Ride IS

In this review the Brooks Womens Glycerin GTS 22 emerges as a choice for runners and gym goers who prioritize plush cushioning and reliable stabilization. The single biggest reason to buy is the shoe's combination of DNA Tuned cushioning and GuideRails support, which together deliver soft landings and controlled motion through toe-off. Reviewers will find the GTS 22 especially noteworthy for its diabetic-friendly certification and an accommodating knit upper that balances breathability with a secure fit.

Key Features

• GuideRails support: Keeps excess motion in check to help stabilize the foot during long runs or cross training sessions.
• DNA Tuned cushion: Larger heel cells provide plush landings while smaller forefoot cells deliver a responsive toe-off for smoother transitions.
• Accommodating fit: The double jacquard knit upper flexes with the foot for comfort while maintaining breathability and durability.
• Smoother transitions: A broad platform and tuned heel and forefoot help steady heel-to-toe movement for a controlled ride.
• Diabetic-friendly: Certified PDAC A5500, making it suitable for buyers seeking extra interior room and protective design.

Who It's For

The Glycerin GTS 22 is ideal for road runners and gym users who want luxurious cushioning paired with supportive guidance through the stride; it works well for those who need extra stability without sacrificing softness. The shoe also appeals to buyers looking for a certified diabetic option and anyone who values a breathable knit upper for daily wear.

Runners who need a very wide toe box or prefer a minimalist, low-cushion ride should look elsewhere, as some customers find the toe box a touch narrow and the plush midsole too soft for tempo racing. Those seeking a neutral-only feel may prefer the non-GTS Glycerin 22 instead.

Pros & Cons

Pros

• Exceptional cushioning that absorbs impact and supports long runs.
• GuideRails system offers noticeable support for excess motion without feeling restrictive.
• Comfortable, breathable double jacquard knit upper that adapts to the foot.
• PDAC A5500 certification makes it a practical pick for diabetic foot care needs.

Cons

• Some users report the toe box can feel narrow, so fit may vary between customers.
• Higher price point may give mixed opinions about value for money among buyers.

Specifications

Model	Glycerin GTS 22
Support System	GuideRails holistic support
Midsole Technology	DNA Tuned dual-cell cushioning
Upper	Double jacquard knit for flexibility and breathability
Use Case	Road running, cross training, gym
Diabetic Certification	PDAC A5500 certified
Predecessor	Glycerin GTS 21

Our Verdict

The Brooks Womens Glycerin GTS 22 is a strong choice for runners who want plush cushioning combined with guided stability; the DNA Tuned midsole and GuideRails system create a smooth, controlled ride that works for daily training and long miles. It represents good value for buyers who need support and comfort, though those needing an especially wide toe box or a firmer race shoe may prefer alternatives.

Frequently Asked Questions

Are these shoes good for everyday running?
Yes. The mix of plush cushioning and GuideRails support makes them suitable for daily road running, gym sessions, and cross training.

Do they run true to size?
Fit varies; many find the knit upper accommodating, but some customers report the toe box feels narrow, so trying on or checking return options is recommended.

Are these shoes safe for diabetic feet?
Yes. The Glycerin GTS 22 is PDAC A5500 certified, indicating it meets standards for diabetic-friendly footwear.