Brooks Womens Glycerin GTS 22 Supportive Running Shoe - Smooth Stable

Our review of the Brooks Womens Glycerin GTS 22 finds it best suited for runners and active women who prioritize plush cushioning with added stability. The single biggest reason to consider these shoes is the combination of Brooks DNA Tuned midsole cushioning and GuideRails support, which together deliver soft landings and controlled motion during road runs, gym sessions, or long days on your feet. Fit can vary by foot shape, so expect an accommodating knit upper but mixed reports on toe box width and cushioning feel.

Key Features

• GuideRails support: Keeps excess motion in check to help stabilize the knee and reduce strain during long runs or cross training.
• DNA Tuned cushion: Larger heel cells give plush landings while smaller forefoot cells enable responsive toe-offs for smoother transitions.
• Accommodating double jacquard knit: The engineered upper stretches where needed for breathability and a more comfortable fit across the midfoot.
• Broad platform: Stabilizes the foot and works with the tuned heel and forefoot to create consistent heel-to-toe movement.
• Certified diabetic option: The Glycerin GTS 22 is a PDAC A5500 certified diabetic shoe, making it a consideration for shoppers needing that clearance.

Who It's For

The Glycerin GTS 22 is designed for women who want a luxurious, cushioned ride but need added support to limit excess motion, so it fits long-distance road runners, walkers with mild pronation, and active gym users well. It also appeals to anyone looking for a stable platform that still feels soft underfoot.

Shoppers who prefer a very wide toe box or a firmer, minimally cushioned shoe should look elsewhere, as customer feedback shows mixed opinions on toe-room and cushioning firmness, and those seeking a neutral-only, lighter trainer may prefer the non-GTS Glycerin 22.

Pros & Cons

Pros

• Supportive GuideRails system reduces excess motion and helps protect joints during repetitive movement.
• Plush but responsive DNA Tuned midsole balances soft landings with energetic toe-offs.
• Comfortable, breathable knit upper that adapts to foot shape for much of the length of wear.

Cons

• Fit and toe-box width receive mixed feedback, so some may find the front of the shoe too narrow.

Specifications

Brand	Brooks
Model	Glycerin GTS 22 (women)
Support system	GuideRails holistic support
Midsole technology	DNA Tuned with dual-size cells
Upper	Double jacquard knit
Best for	Road running, cross training, gym, walking
Certification	PDAC A5500 diabetic shoe

Our Verdict

The Brooks Glycerin GTS 22 is a strong choice for women wanting plush cushioning plus dependable support; its DNA Tuned midsole and GuideRails system justify choosing the GTS over the neutral Glycerin for those who need stabilization. It represents good value for runners and walkers who prioritize comfort and joint protection, though those needing a very roomy toe box should try before they buy.

Frequently Asked Questions

Are these shoes good for long road runs?
Yes, the combination of plush DNA Tuned cushioning and a broad platform makes them comfortable for long road runs while helping stabilize gait.

Do they fit wide feet comfortably?
The engineered knit upper is accommodating, but customer reports on toe-box width are mixed, so trying them on is recommended if you have very wide toes.

Is this model different from the Glycerin 22?
Yes, the GTS 22 adds GuideRails support for extra stabilization compared with the neutral Glycerin 22.