Brooks Womens Glycerin GTS 22 Supportive Running Shoe - Smooth Support

In this review of the Brooks Womens Glycerin GTS 22 Supportive Running Shoe the bottom line is simple: this is a cushioned, stability-focused road runner for women who need extra support without sacrificing plush comfort. The shoe's standout feature is its GuideRails support, which limits excess motion while letting the foot move naturally, and combined with the updated DNA Tuned midsole it produces soft landings and responsive toe-offs. Runners seeking relief from foot pain or those who want a roomy, breathable upper will find much to like here.

Key Features

• GuideRails support: Keeps excess motion at bay to stabilize the knee and foot during runs and cross training sessions.
• DNA Tuned cushion: Larger heel cells deliver plush landings while smaller forefoot cells give a livelier toe-off for smoother transitions.
• Accommodating fit: The double jacquard knit upper stretches where needed and breathes well to reduce hot spots on longer outings.
• Broad platform: A wider base increases stability for steady heel-to-toe motion on road runs and gym work.
• Certified diabetic friendly: The Glycerin GTS 22 is a PDAC A5500 certified diabetic shoe for users needing extra foot protection and comfort.

Who It's For

The Glycerin GTS 22 is aimed at women who want generous cushioning plus structured support - ideal for neutral-to-mildly overpronating runners, walkers who need stability, and anyone who experiences foot pain that improves with arch support. It also suits cross training and gym days where a smooth, stable platform helps with multi-directional movements.

Runners who prefer minimal shoes, extremely narrow toe boxes, or a very snappy, racing-oriented ride should look elsewhere; this model favors plush comfort and stability over a fast, lightweight feel.

Pros & Cons

Pros

• Excellent overall comfort and arch support that many buyers report relieves foot, hip, and back discomfort.
• Balanced cushioning from the DNA Tuned midsole that blends soft landings with responsive toe-offs.
• Supportive GuideRails system that stabilizes motion without feeling restrictive.
• Breathable, flexible double jacquard knit upper for an accommodating fit.

Cons

• Fit and toe box feel are mixed among users - some find plenty of room while others feel the forefoot is narrow.
• Heavier, more cushioned design may not appeal to runners seeking a minimalist or racing shoe.

Specifications

Our Verdict

The Brooks Glycerin GTS 22 is a strong choice for women wanting plush cushioning with structured support; its GuideRails and DNA Tuned midsole deliver smooth, stable transitions and can help reduce foot-related pain. It represents good value for runners who prioritize comfort and stability over a lightweight, racing feel.

Frequently Asked Questions

Are these shoes good for overpronation?
Yes, the GuideRails system is designed to control excess motion and is suitable for mild to moderate overpronation.

Do they run true to size?
Sizing feedback is mixed; many find the length true but toe box width varies, so try on if possible or consider half sizes if between sizes.

Can I use these for everyday walking and standing?
Yes, the cushioned DNA Tuned midsole and supportive platform make them comfortable for long periods of walking and standing.