Brooks Womens Glycerin GTS 22 Supportive Running Shoe - Smooth THIS

In this review the Brooks Womens Glycerin GTS 22 stands out as a supportive, highly cushioned road running shoe built for women who want soft landings and controlled motion. The single biggest reason to buy is the combination of DNA Tuned cushion for plush heel strikes and responsive toe-offs together with the GuideRails support system that keeps excess movement in check, making it a strong choice for long miles, recovery runs and anyone seeking extra stability without a heavy, clinical feel.

Key Features

• GuideRails support: Keeps excess motion at bay so the foot and body move along a natural path, reducing strain during long runs and cross training.
• DNA Tuned cushion: Larger midsole cells in the heel provide soft, plush landings while smaller forefoot cells deliver a responsive toe-off for smoother transitions.
• Accommodating fit: The double jacquard knit upper stretches where needed and breathes well, offering a combination of comfort and durability.
• Stable platform: A broad base stabilizes the foot through heel-to-toe motion, which helps road runners feel balanced on varied paces.
• Diabetic shoe certification: Certified PDAC A5500, making it appropriate for buyers who need footwear that meets diabetic shoe guidelines.

Who It's For

The Glycerin GTS 22 is best for women who prioritize cushioning and supportive stability on the road, including recovery runners, daily trainers and those who appreciate a plush feel without sacrificing smooth transitions. It also suits gym-goers or cross trainers who want extra midsole protection and controlled motion.

Runners who prefer a very wide toe box or a minimalist, low-drop shoe should look elsewhere, as some customers report the toe box feels narrow and the shoe is built around a more structured, supportive platform rather than a barefoot feel.

Pros & Cons

Pros

• Exceptional cushioning from DNA Tuned for soft landings and energized toe-offs.
• Support thanks to GuideRails that limit excess motion and improve stability.
• Comfortable, breathable upper with an accommodating fit for many foot shapes.
• Certified PDAC A5500 for those needing diabetic-friendly footwear.

Cons

• Some users find the toe box too narrow, so those needing roomy forefoot space may be disappointed.
• Not the lightest option if a minimal weight is a top priority for fast race days.

Specifications

Brand	Brooks
Model	Glycerin GTS 22
Support Type	GuideRails holistic support
Cushioning	DNA Tuned midsole with dual-size cells
Upper	Double jacquard knit, breathable and flexible
Use	Road running, cross training, gym
Certification	PDAC A5500 diabetic shoe

Our Verdict

The Brooks Womens Glycerin GTS 22 is a strong pick for women seeking a plush, stable daily trainer that balances soft cushioning with motion control. Its DNA Tuned midsole and GuideRails support make it worthwhile for runners who value comfort and injury-conscious stability, though those needing an extra-wide toe box or the lightest race shoe should consider other options.

Frequently Asked Questions

Are these shoes good for long runs?
Yes, the combination of DNA Tuned cushioning and a stable platform makes them well suited to long road runs and high-mileage training.

Do they run true to size?
Customer opinions vary; some find the fit true while others report a narrower toe box, so trying them on or ordering two sizes to compare is wise.

Can diabetics use these shoes?
Yes, the Glycerin GTS 22 is certified PDAC A5500 and meets diabetic shoe guidelines for appropriate footwear.