Brooks Womens Glycerin GTS 22 Supportive Running Shoe - Stable Cushion

In this review the Brooks Womens Glycerin GTS 22 is presented as a comfortable, stability-focused road running shoe for women who want plush cushioning without losing control. The single biggest reason to buy is the combination of Brooks DNA Tuned midsole and GuideRails support, which together create luxurious heel cushioning and guided, stable transitions. Reviewers note the shoe excels at long runs, gym sessions, and everyday wear where support and cushioning are priorities, though some runners should check fit before committing.

Key Features

• DNA Tuned Cushion: Larger midsole cells in the heel provide soft, plush landings while smaller forefoot cells deliver responsive toe-offs for smooth propulsion.
• GuideRails Support: A holistic support system that keeps excess motion in check to stabilize the foot through the gait cycle and reduce strain on joints.
• Accommodating Fit: The double jacquard knit upper stretches where needed for breathability and durability, adapting to common foot shapes for comfort.
• Smooth Transitions: A broad platform and tuned heel-to-toe geometry smooth the roll from heel strike to toe-off for predictable road running.
• Diabetic Friendly: Certified as a PDAC A5500 Diabetic shoe, offering an option for walkers or runners who need extra foot care considerations.

Who It's For

The Glycerin GTS 22 is best for women who prioritize cushioning plus guidance: long-distance road runners, gym goers who want extra stability, and anyone who values a plush ride with reduced excess motion. Its supportive GuideRails make it particularly helpful for runners who experience mild pronation or want added lateral control during cross training.

Runners who prefer a very wide toe box or consistently need a roomy fit may want to try these on first or consider a different model, because some customers report a narrower toe area and that the shoe can run small for certain foot shapes.

Pros & Cons

Pros

• Plush, well tuned cushioning that absorbs impact and aids in comfortable long runs.
• GuideRails support helps stabilize the foot and reduce unwanted motion during activity.
• Breathable knit upper balances durability with an accommodating feel.

Cons

• Fit varies by user; a number of customers find the toe box narrow and recommend trying a half size up if between sizes.

Specifications

Model	Glycerin GTS 22
Target	Women
Support System	GuideRails holistic support
Midsole Technology	DNA Tuned with dual-size cells
Upper	Double jacquard knit
Use	Road running, cross training, gym
Special Cert	PDAC A5500 Diabetic shoe

Our Verdict

The Glycerin GTS 22 is an excellent choice for women seeking a plush, stable running shoe that performs well on roads and in the gym; its DNA Tuned cushion and GuideRails support justify the investment for runners who value comfort and joint-friendly transitions. Try before you buy if you are between sizes or need extra toe-box room.

Frequently Asked Questions

Are these shoes good for long runs?
Yes, the DNA Tuned cushioning and broad platform deliver plush shock absorption and smooth heel-to-toe transitions suited to longer distances.

Do they offer support for overpronation?
Yes, the GuideRails system provides holistic support that helps control excess motion and offers added stability during runs.

How should I size these?
Customers report mixed fit; consider trying your normal size but try a half size up if you have a wider forefoot or are between sizes.