Brooks Womens Glycerin GTS 22 Supportive Running Shoe - Stable IS

In this review the Brooks Womens Glycerin GTS 22 stands out as a cushioned, supportive road running shoe for women who prioritize stability and comfort. The single biggest reason to consider the Glycerin GTS 22 is its combination of plush, responsive DNA Tuned cushioning with the GuideRails support system, which together deliver smooth heel-to-toe transitions while keeping excess motion in check. This model is also a certified PDAC A5500 diabetic shoe, so it suits runners and walkers who need an accommodating, protective fit.

Key Features

• GuideRails support: Keeps excess motion in check to help stabilize the foot and reduce strain on the knees and hips during runs or daily wear.
• DNA Tuned cushion: Larger heel cells provide soft landings while smaller forefoot cells create energetic toe-offs for a balanced ride.
• Accommodating fit: The double jacquard knit upper flexes with the foot for breathability and a comfortable, roomy feel in many foot shapes.
• Smooth transitions: A broad platform and tuned heel-to-forefoot geometry promote stable, seamless movement from strike to push-off.
• Diabetic friendly: Certified PDAC A5500 designation indicates suitability for users needing extra protective, therapeutic footwear.

Who It's For

The Glycerin GTS 22 is best for women seeking a supportive, cushioned shoe for road running, cross training, gym sessions, or everyday walking. Runners who experience minor hip or back discomfort and want extra stability from a shoe that tames excess motion will appreciate the GuideRails system and broad platform.

Those who prefer a minimalist, very narrow racer or want an aggressive, low-drop speed shoe should look elsewhere; the Glycerin GTS 22 favors plush cushioning and stability over minimal stack height or a racing feel. Also, shoppers who need exacting size fits should try them on when possible, as customer feedback on toe box width and overall cushioning varies.

Pros & Cons

Pros

• Generous cushioning with responsive transitions thanks to DNA Tuned cells.
• GuideRails provide tangible support that reduces excess motion and helps relieve foot pain.
• Comfortable, breathable double jacquard knit upper gives an accommodating fit for many feet.

Cons

• Sizing and toe box width receive mixed feedback, so fit can feel roomy to some and narrow to others.
• Cushioning preference is subjective; a few users may find it either firmer or softer than expected.

Specifications

Brand	Brooks
Model	Glycerin GTS 22
Support	GuideRails holistic support system
Cushioning	DNA Tuned midsole with varied cell sizes
Upper	Double jacquard knit for flexibility and breathability
Ideal use	Road running, cross training, gym, everyday walking
Special	Certified PDAC A5500 diabetic shoe

Our Verdict

The Brooks Womens Glycerin GTS 22 is a strong choice for women who want plush, stable cushioning and holistic support for road runs and daily wear. Its DNA Tuned midsole and GuideRails system deliver smooth, controlled transitions and meaningful relief for those with foot or gait concerns, making it good value for buyers seeking comfort plus stability rather than minimal racing performance.

Frequently Asked Questions

Are these shoes good for overpronation?
Yes; the GuideRails support system helps control excess motion and is intended to assist runners who overpronate or need added stability.

Do they run true to size?
Fit feedback is mixed: many users find an accommodating fit, but some report the toe box feels narrow, so try them on if possible.

Can I use these for everyday walking and gym work?
Yes; the broad platform, cushioning, and support make them suitable for road running, gym sessions, and daily walking.