Brooks Womens Glycerin GTS 22 Supportive Running Shoe (Style 7R7M)

In this review the Brooks Womens Glycerin GTS 22 is presented as a cushioned, stability-focused running shoe for women who want plush landings without sacrificing a responsive toe-off. The single biggest reason to buy is the combination of Brooks DNA Tuned cushion and GuideRails support, which together deliver soft heel strikes and guided, stable transitions for road running, gym sessions, or daily wear. The shoe is also notable as a certified PDAC A5500 diabetic option for those needing extra accommodation.

Key Features

• GuideRails support: Keeps excess motion in check to help stabilize the foot and reduce strain on the knees during runs and cross training.
• DNA Tuned cushion: Larger midsole cells in the heel give plush landings while smaller forefoot cells provide a responsive toe-off for smoother transitions.
• Accommodating fit: The double jacquard knit upper stretches where needed for comfort while remaining breathable and durable for longer sessions.
• Broad platform: A wider base stabilizes the foot through heel-to-toe movement, making transitions feel balanced and controlled.
• Certified diabetic option: The shoe is PDAC A5500 certified, indicating it meets standards for diabetic footwear needs and extra accommodation.

Who It's For

The Glycerin GTS 22 is best for women who prioritize cushioning and support over minimalist feel, including road runners who appreciate a plush heel and runners who benefit from added stabilization. It also suits gym-goers and people who want a comfortable, stable daily trainer with good arch support.

Runners seeking an ultra-light, barefoot-like shoe or a very roomy toe box should look elsewhere, since some users report a snug toe fit. Those who need a racing flat or minimal shoe will find the Glycerin GTS 22 too cushioned and structured for speed-focused sessions.

Pros & Cons

Pros

• Excellent cushioning and support that many customers describe as life-changing for comfort and arch support.
• GuideRails system reduces excess motion for smoother, more stable runs.
• Accommodating knitted upper balances breathability with a secure fit for day-long wear.
• PDAC A5500 certification makes it suitable for those needing diabetic-friendly footwear.

Cons

• Some customers find the toe box narrow, so sizing or width preferences may vary.
• Not ideal for runners wanting a minimal or ultra-light racing shoe due to plush cushioning and support structure.

Specifications

Model	Glycerin GTS 22
Support system	GuideRails holistic support
Cushion technology	DNA Tuned midsole with dual-size cells
Upper	Double jacquard knit, breathable and flexible
Intended use	Road running, cross training, gym, everyday wear
Diabetic certification	PDAC A5500 certified
Predecessor	Glycerin GTS 21

Our Verdict

The Brooks Glycerin GTS 22 is a strong choice for women who want plush cushioning paired with purposeful support; the DNA Tuned midsole and GuideRails system create smooth, stable transitions suited to daily training and longer runs. It represents good value for runners prioritizing comfort and joint protection, though those needing an extra roomy toe box or minimal racer should test fit carefully before buying.

Frequently Asked Questions

Do these run true to size?
Fit varies by foot shape; many find the length true but some report a narrow toe box, so consider trying your usual size and testing width.

Are these suitable for diabetic feet?
Yes, the shoe is PDAC A5500 certified, indicating it meets guidelines for diabetic-friendly footwear and extra accommodation.

Is this shoe good for speedwork?
Not ideal for dedicated speed sessions or racing flats due to its plush cushioning and supportive structure, but it is fine for easy to moderate tempo runs.